Recombinant Human Membrin His Protein

SDS-Page: Membrin Protein [NBP2-23085]

• Reactivity: Hu
• Applications: PAGE
• Concentration: 0.25 mg/ml

Recombinant Human Membrin His Protein Summary

• Description: A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-190 of Human Membrin
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDPLFQQ THKQVHEIQS CMGRLETADK QSVHIVENEI QASIDQIFSR LERLEILSSK EPPNKRQNAR LRVDQLKYDV QHLQTALRNF QHRRHAREQQ ERQREELLSR TFTTNDSDTT IPMDESLQFN SSLQKVHNGM DDLILDGHNI LDGLRTQRLT LKGTQKKILD IANMLGLSNT VMRLIEKRAF QDK

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: GOSR2
• Purity: >85%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Application Notes: Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.
• Theoretical MW: 24.6 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 1 M UREA, 10% glycerol
• Preservative: No Preservative
• Concentration: 0.25 mg/ml
• Purity: >85%, by SDS-PAGE

Alternate Names for Recombinant Human Membrin His Protein

• golgi SNAP receptor complex member 2
• GS27Bos1,27 kDa Golgi SNARE protein
• membrin

Background

Golgi SNAP receptor complex member 2 isoform A, also known as GOSR2, belongs to the SNARE protein family and are important trafficking proteins between the endoplasmic reticulum and the Golgi and between Golgi subcompartments. This protein exists as cytoplasmically oriented integral membrane proteins. The human GOSR2 gene, which maps to chromosome 17q21, is located near a locus implicated in familial essential hypertension, indicating that it is a potential candidate gene for this disease. Recombinant human GOSR2 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: GOSR2