KvBeta1 Antibody (OTI4E7) [DyLight 650]

• Reactivity: Hu, Mu, Rt
• Applications: IHC
• Clone: OTI4E7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 650

KvBeta1 Antibody (OTI4E7) [DyLight 650] Summary

• Immunogen: Full length recombinant protein of human KvBeta1 (NP_751891) produced in HEK293T cells.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: KCNAB1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for KvBeta1 Antibody (OTI4E7) [DyLight 650]

• AKR6A3
• hKvb3
• hKvBeta3
• K(+) channel subunit beta-1
• KCNA1Bpotassium channel beta 3 chain
• Kvb1.3
• KV-BETA-1
• potassium channel beta3 subunit
• potassium channel shaker chain beta 1a
• potassium voltage-gated channel beta subunit
• potassium voltage-gated channel, shaker-related subfamily, beta member 1
• voltage-gated potassium channel beta-1 subunit
• voltage-gated potassium channel subunit beta-1

Background

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNAB1