H60 Antibody [Alexa Fluor® 532]

Images

 
There are currently no images for H60 Antibody (AF1155X).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, B/N
Clonality
Polyclonal
Host
Goat
Conjugate
Alexa Fluor 532

Order Details

H60 Antibody [Alexa Fluor® 532] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse H60
Asp30-Gln212
Accession # Q3TDZ7
Specificity
Detects mouse H60 in direct ELISAs and Western blots.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Blockade of Receptor-ligand Interaction
  • Flow Cytometry
  • Western Blot

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
Buffer
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for H60 Antibody [Alexa Fluor® 532]

  • H60
  • H60a

Background

H60 was originally described as an immunodominant histocompatibility antigen that is expressed in BALB mice but not in B6 mice. More recently it was reported to function as a ligand for mouse NKG2D, an activating receptor found on NK cells, on some T cell subsets, and on stimulated macrophages. H60 shares approximately 25 percent amino acid identity with the Rae-1 family, a small group of proteins that also function as ligands for mouse NKG2D. H60 and the Rae-1 proteins are distantly related to MHC class I proteins, but they possesses only the alpha 1 and alpha 2 Ig-like domains, and have no capacity to bind peptide or interact with beta 2‑microglobulin. The genes encoding these proteins are not found within the Major Histocompatibility Complex on mouse chromosome 17, but rather map to mouse chromosome 10. Unlike the GPI-linked Rae-1 proteins, H60 appears to be anchored to the membrane via a hydrophobic transmembrane segment. H60 transcripts were found in embryonic tissue, in spleen, and in some transformed cell lines. Transcripts were also observed in mouse skin cells after exposure to carcinogens. Binding of H60 to NKG2D results in the activation of cytolytic activity and/or cytokine production by the NKG2D-expressing effector cells. Ectopic expression of H60 on mouse tumor cell lines resulted in the in vivo rejection of the tumors (1‑6).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

MAB139
Species: Hu
Applications: CostimT, CyTOF-ready, Flow, Neut, WB
202-IL
Species: Hu
Applications: BA
NBP1-71691
Species: Hu, Mu
Applications: ICC/IF, IHC,  IHC-P, WB
NBP2-43666
Species: Hu, Rt
Applications: ICC/IF, IHC,  IHC-P, WB
MAB8526
Species: Mu
Applications: IHC
NBP1-88347
Species: Hu, Mu
Applications: ICC/IF, IHC,  IHC-P, KD, WB
AF1155X
Species: Mu
Applications: WB, Flow, B/N

Publications for H60 Antibody (AF1155X) (0)

There are no publications for H60 Antibody (AF1155X).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for H60 Antibody (AF1155X) (0)

There are no reviews for H60 Antibody (AF1155X). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for H60 Antibody (AF1155X) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our H60 Antibody [Alexa Fluor® 532] and receive a gift card or discount.