GNAI3 Antibody - Azide and BSA Free

Product Discontinued

GNAI3 Antibody - Azide and BSA Free Summary

• Immunogen: KNNLKECGLY, corresponding to amino acids 345-354 of GAI3.
• Localization: Cell Membrane
• Specificity: recognises GNAI3.
• Predicted Species: Chicken (100%), Hamster (100%), Guinea Pig (100%). Backed by our 100% Guarantee.
• Clonality: Polyclonal
• Host: Chicken
• Gene: GNAI3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:200 - 1:500
  • Western Blot 1:200 - 1:500
• Application Notes: ICC: Use at a dilution of 1/200. Western Blot: Use at a dilution of 1/1000. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa). tissue and cell immunostaining: Use at a starting dilution of 1/500. Optimal dilutions/concentrations should be determined by the end user.
• Control:

  RGS19 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.02% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Notes

Chicken products cannot be exported to Canada.

Alternate Names for GNAI3 Antibody - Azide and BSA Free

• FLJ26559
• G(i) alpha-3
• guanine nucleotide binding protein (G protein), alpha inhibiting activitypolypeptide 3,87U6
• guanine nucleotide-binding protein G(k) subunit alpha

Background

GAI3 is the a subunit of inhibitory trimeric G protein (Gi), which inhibits adenylate cyclase once its G protein coupled receptors (GPCR) such as a2 adrenergic receptors are activated. GAI3 can be inactivated by pertussis toxin. Guanine nucleotide binding proteins are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor regulated K(+) channels.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GNAI3
• Entrez:
  • 2773(Human)
  • 56470(Mouse)
  • 59293(Rat)