EMR2 Antibody

Immunohistochemistry-Paraffin: EMR2 Antibody [NLS6319] - Analysis of anti-EMR2 antibody with human lung, pneumonia, neutrophils.

Product Discontinued

EMR2 Antibody Summary

• Immunogen: Synthetic 18 amino acid peptide from N-terminal extracellular domain of human EMR2.
• Specificity: Human EMR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Primate (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ADGRE2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 3 - 17 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for EMR2 Antibody

• CD312
• DKFZp781B135
• egf-like module containing, mucin-like, hormone receptor-like 2
• egf-like module containing, mucin-like, hormone receptor-like sequence 2
• EGF-like module receptor 2
• EGF-like module-containing mucin-like hormone receptor-like 2
• EMR2

Background

EMR2 is an Orphan-B GPCR with an unknown ligand. EMR2 has five EGF-like domains in the extracellular domain and is highly homologous to CD97. Multiple isoforms of EMR2 are produced by alternative splicing. EMR2 has been reported to be expressed in immune tissues, where it has been shown to be restricted specifically to monocytes and granulocytes. ESTs have been isolated from blood, colon, lymph node, placenta, spleen, testis, and uterus libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADGRE2
• Entrez:
  • 30817(Human)