EMR2 Antibody (DMC370) - Chimeric

• Reactivity: Hu
• Applications: Flow
• Clone: DMC370
• Clonality: Monoclonal
• Host: Human
• Conjugate: Unconjugated
• Concentration: LYOPH

EMR2 Antibody (DMC370) - Chimeric Summary

• Description: This product is shipped at ambient temperature. Store at -20C to -80C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80C (Avoid repeated freezing and thawing).
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: EMR2 recombinant protein expressed in mammalian cells (Accession# Q9UHX3). The exact amino acid sequence is proprietary.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Gene: ADGRE2
• Purity: Antigen Affinity-purified from cell culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:100

Packaging, Storage & Formulations

• Storage: Store at -20C in powder form. Store at -80C once reconstituted.
• Buffer: PBS, pH 7.4, 5-8% Trehalose
• Preservative: Trehalose
• Concentration: LYOPH
• Purity: Antigen Affinity-purified from cell culture supernatant
• Reconstitution Instructions: Dissolve the lyophilized antibody in sterile and low endotoxin water. The recommend volume of water is lot specific. Please refer to the instructions printed on the product vial or contact technical support.

Alternate Names for EMR2 Antibody (DMC370) - Chimeric

• CD312
• DKFZp781B135
• egf-like module containing, mucin-like, hormone receptor-like 2
• egf-like module containing, mucin-like, hormone receptor-like sequence 2
• EGF-like module receptor 2
• EGF-like module-containing mucin-like hormone receptor-like 2
• EMR2

Background

EMR2 is an Orphan-B GPCR with an unknown ligand. EMR2 has five EGF-like domains in the extracellular domain and is highly homologous to CD97. Multiple isoforms of EMR2 are produced by alternative splicing. EMR2 has been reported to be expressed in immune tissues, where it has been shown to be restricted specifically to monocytes and granulocytes. ESTs have been isolated from blood, colon, lymph node, placenta, spleen, testis, and uterus libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADGRE2