DPP9 Antibody (757004) [Alexa Fluor™ Plus 680]

• Reactivity: Hu
• Clone: 757004
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 680

DPP9 Antibody (757004) [Alexa Fluor™ Plus 680] Summary

• Specificity: Detects human DPP9 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) DPPIV/CD26 or rhDPP10 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DPP9 Antibody (757004) [Alexa Fluor™ Plus 680]

• dipeptidyl peptidase 9
• Dipeptidyl peptidase IV-related protein 2
• dipeptidyl peptidase IV-related protein-2
• Dipeptidyl peptidase IX
• Dipeptidyl peptidase-like protein 9
• dipeptidylpeptidase 9
• dipeptidyl-peptidase 9
• DKFZp762F117
• DP9
• DPLP9
• DPP IX
• DPP9
• DPRP2
• DPRP-2
• EC 3.4.14.5
• FLJ16073

Background

DPP9 is a member of the S9b family of serine peptidases (1, 2). It shares 19% amino acid identity with DPP4 and 58% amino acid identity with DPP8. It exhibits post‑proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-terminus of oligo- and polypeptides (3). Unlike DPP4, DPP9 does not appear to be membrane bound and is localized exclusively in the cytoplasm (4). This family of proline-specific dipeptidyl peptidases has been implicated in a variety of diseases including type 2 diabetes, obesity and cancer, and has been a potential target for drug discovery (5, 6).

1. Olsen, C. and Wagtmann, N. (2002) Gene 299:185.
2. Qi, S.Y. et al. (2003) Biochem. J. 373:179.
3. Bjelke, J.R. et al. (2006) Biochem. J. 396:391.
4. Ajami, K. et al. (2004) Biochim. Biophys. Acta. 1679:18.
5. Rosenblum, J.S. and Kozarich, J.W. et al. (2003) Curr. Opin. Chem. Biol. 7:496.
6. Van der Veken, P. et al. (2007) Curr. Top. Med. Chem. 7:621.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.