Immunogen | Recombinant human DOG-1 protein |
Localization | Cell Surface and Cytoplasmic |
Marker | Gastrointestinal Stromal Tumor Marker |
Specificity | Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%. |
Isotype | IgG1 Kappa |
Clonality | Monoclonal |
Host | Mouse |
Gene | ANO1 |
Purity | Protein A or G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Storage | Store at 4C in the dark. |
Buffer | PBS |
Preservative | 0.05% Sodium Azide |
Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Alexa Fluor 350 | NBP2-34603AF350 | |
Alexa Fluor 405 | NBP2-34603AF405 | |
Alexa Fluor 488 | NBP2-34603AF488 | |
Alexa Fluor 532 | NBP2-34603AF532 | |
Alexa Fluor 594 | NBP2-34603AF594 | |
Alexa Fluor 647 | NBP2-34603AF647 | |
Alexa Fluor 700 | NBP2-34603AF700 | |
Alexa Fluor 750 | NBP2-34603AF750 | |
Biotin | NBP2-34603B | |
DyLight 350 | NBP2-34603UV | |
DyLight 405 | NBP2-34603V | |
DyLight 488 | NBP2-34603G | |
DyLight 550 | NBP2-34603R | |
DyLight 594 | NBP2-34603DL594 | |
DyLight 650 | NBP2-34603C | |
DyLight 680 | NBP2-34603FR | |
DyLight 755 | NBP2-34603IR | |
FITC | NBP2-34603F | |
HRP | NBP2-34603H | |
Janelia Fluor 549 | NBP2-34603JF549 | |
Janelia Fluor 646 | NBP2-34603JF646 |
Diseases for DOG1/TMEM16A Antibody (NBP2-34603PCP)Discover more about diseases related to DOG1/TMEM16A Antibody (NBP2-34603PCP).
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PTMs for DOG1/TMEM16A Antibody (NBP2-34603PCP)Learn more about PTMs related to DOG1/TMEM16A Antibody (NBP2-34603PCP).
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Gene Symbol | ANO1 |