DOG1/TMEM16A Antibody (DG1/447) [PerCP]

Product Discontinued

DOG1/TMEM16A Antibody (DG1/447) [PerCP] Summary

• Immunogen: Recombinant human canine1/TMEM16A protein (Uniprot: Q5XX6)
• Localization: Cell Surface and Cytoplasmic
• Marker: Gastrointestinal Stromal Tumor Marker
• Specificity: Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: ANO1
• Purity: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for DOG1/TMEM16A Antibody (DG1/447) [PerCP]

• ANO1
• anoctamin 1
• DOG1
• ORAOV2
• TAOS2
• TMEM16A

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ANO1