Cbx2 Antibody (880833) [PE]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 880833
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: PE

Cbx2 Antibody (880833) [PE] Summary

• Immunogen: E. coli-derived recombinant human Cbx2
  Lys131-His217
  Accession # Q14781
• Specificity: Detects human Cbx2 in ELISA.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CBX2
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for Cbx2 Antibody (880833) [PE]

• Cbx2
• CDCA6
• cell division cycle associated 6
• chromobox homolog 2 (Drosophila Pc class)
• chromobox homolog 2 (Pc class homolog, Drosophila)
• chromobox homolog 2
• chromobox protein homolog 2
• M33
• MGC10561
• modifier 3
• Pc class homolog
• SRXY5

Background

Polycomb' genes in Drosophila maintain the repressed state of homeotic and other developmentally regulatedgenes (Wedeen et al., 1986 (PubMed 3081265); Kuziora and McGinnis, 1988 (PubMed 2903050)) by mediating changes inhigher-order chromatin structure (Paro and Hogness, 1991 (PubMed 1898775)). M33, a mouse homolog of polycomb, wasisolated by means of the structural similarity of its chromodomain (Pearce et al., 1992 (PubMed 1352241)). The fifthexon of M33 contains a region of homology shared by Drosophila and Xenopus. In Drosophila, its deletion results in theloss of polycomb function.(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CBX2