Cadherin-23 Antibody - BSA Free

Immunohistochemistry: Cadherin-23 Antibody - BSA Free [NBP3-47658] - Immunohistochemical of paraffin-embedded human stomach using (Cadherin-23 antibody) at dilution of 1:100

Western Blot: Cadherin-23 Antibody - BSA Free [NBP3-47658] - A172 cells were subjected to SDS PAGE followed by western blot with (Cadherin-23 antibody) at dilution of 1:1000

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Cadherin-23 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Cadherin-23 Antibody - BSA Free (NBP3-47658) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: cadherin-like 23. (Uniprot# Q9H251)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CDH23
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:100 - 1:200
  • Western Blot 1:500 - 1:2000
• Theoretical MW: 59 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Cadherin-23 Antibody - BSA Free

• cadherin related 23
• cadherin-23
• cadherin-like 23
• cadherin-related 23
• cadherin-related family member 23
• CDHR23
• DKFZp434P2350
• FLJ00233
• FLJ36499
• KIAA1774
• KIAA1812
• MGC102761
• otocadherin
• USH1D

Background

CDH23 is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is a large, single-pass transmembrane protein composed of an extracellular domain containing 27 repeats that show significant homology to the cadherin ectodomain. Expressed in the neurosensory epithelium, the protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Two alternative splice variants have been identified that encode different isoforms. Additional variants have been observed but their full-length nature has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDH23