ASB8 Antibody - BSA Free

ASB8 Antibody [NBP1-83620] -Staining of human tonsil shows moderate cytoplasmic positivity in germinal and non germinal center cells.

ASB8 Antibody [NBP1-83620] -Staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells

ASB8 Antibody [NBP1-83620] - Staining of human cerebellum shows moderate cytoplasmic positivity in purkinje cells.

Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

• Reactivity: Hu, Mu, Rt
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

ASB8 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit ASB8 Antibody - BSA Free (NBP1-83620) is a polyclonal antibody validated for use in IHC and WB. Anti-ASB8 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: QSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNN
• Predicted Species: Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ASB8
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  ASB8 Protein (NBP1-83620PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for ASB8 Antibody - BSA Free

• ankyrin repeat and SOCS box containing 8
• ankyrin repeat and SOCS box protein 8
• ankyrin repeat and SOCS box-containing 8
• ASB-8
• FLJ21255
• MGC5540

Background

ASB8 (Ankyrin repeat and SOCS box protein 8) is a 288 amino acid protein that has its highest level of expression in skeletal muscle. It is also expressed in heart, brain, placenta, liver, kidney and pancreas. ASB8 contains a SOCS box domain suggesting that it may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. It also contains 4 ankyrin repeats which mediate protein-protein interactions and are among the most common structural motifs in known proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ASB8 Antibody (NBP1-83620)(1)

Publication using NBP1-83620

• Mo JS, Chae SC MicroRNA 452 regulates ASB8, NOL8, and CDR2 expression in colorectal cancer cells Genes & genomics 2021-01-01 [PMID: 33398662] (WB)

Bioinformatics

• Gene Symbol: ASB8