AP3M1 Antibody

Western Blot: AP3M1 Antibody [NBP2-27068] - Analysis of human Daudi lysate in the 1) absence and 2) presence of immunizing peptide probed with AP3 antibody at 4 ug/ml.

Immunohistochemistry-Paraffin: AP3M1 Antibody [NBP2-27068] - Formalin-fixed, paraffin-embedded human lung (respiratory epithelium) stained with AP3 antibody at 10 ug/ml.

• Reactivity: Hu, Bv, Ca, Ch, ChHa, Eq, Mu, Rt, Po, Pm, Ma-Op, Pm-Or, Pm, Rb, RM
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

AP3M1 Antibody Summary

• Description: Novus Biologicals Rabbit AP3M1 Antibody (NBP2-27068) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen for this antibody was a portion of amino acid 140-190 of human AP3M1.
• Predicted Species: Mouse (100%), Rat (100%), Porcine (100%), Orangutan (100%), Rabbit (100%), Rhesus Macaque (100%), Opossum (100%), Monkey (100%), Primate (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: AP3M1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10ug/ml
  • Western Blot 3-5ug/ml~

Reactivity Notes

The amino acid sequence used as immunogen for the AP3 antibody is 100% homologous in Macaque.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS and 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein A purified

Alternate Names for AP3M1 Antibody

• adaptor-related protein complex 3, mu 1 subunit
• AP-3 adapter complex mu3A subunit
• MGC22164
• mu-3A subunit
• mu3A-adaptin

Background

Adaptor Protein 3 complex subunit mu-1 (AP3M1) belongs to the adaptor complexes medium subunit family and it contains one MHD (mu homology) domain. AP3 is a hetero-tetrameric protein complex composed of four subunits: two large (delta and beta3), one medium (mu3a/M1), and one small (sigma 3). Mutations in one of the large subunits of AP3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. It is also reported that AP3, is responsible for the trafficking of TLR9 to recognize viral nucleic acid. AP3 is also involved with a susceptibility gene for schizophrenia, dysbindin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AP3M1
• Uniprot:
  • Q9Y2T2(Human)