AP3M1 Antibody (S08-8D2)

Western Blot: AP3M1 Antibody (S08-8D2) [NBP3-14997] - Western blot detection of AP3M1 in K562, C6, 3T3, Hela cell lysates using AP3M1 Rabbit mAb (1:1000 diluted). Predicted band size: 47kDa. Observed band size: 47kDa.

• Reactivity: Hu
• Applications: WB
• Clone: S08-8D2
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

AP3M1 Antibody (S08-8D2) Summary

• Description: Novus Biologicals Rabbit AP3M1 Antibody (S08-8D2) (NBP3-14997) is a recombinant monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthetic peptide of human AP3M1 (Uniprot#: Q9Y2T2)
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: AP3M1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1/1000
• Theoretical MW: 47 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
• Preservative: 0.01% Sodium Azide
• Purity: Affinity purified

Alternate Names for AP3M1 Antibody (S08-8D2)

• adaptor-related protein complex 3, mu 1 subunit
• AP-3 adapter complex mu3A subunit
• MGC22164
• mu-3A subunit
• mu3A-adaptin

Background

The protein encoded by the AP3M1 gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AP3M1