IL-27 Products

Description

IL27 is encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Bioinformatics

Entrez	246778 Human 246779 Mouse
Uniprot	AAH62422 Human AAH62422.1 Human NM_145659 Human NP_663634 Human O35228 Mouse Q8K3I6 Mouse Q8NEV9 Human
Product By Gene ID	246778
Alternate Names	IL-27 p28 subunit IL-27 subunit alpha IL-27 IL27A IL-27-A IL27-A IL27p28 IL30 interleukin 27 interleukin 30 interleukin-27 subunit alpha MGC71873 p28IL-27A

Research Areas for IL-27

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Cell Cycle and Replication

Related IL-27 Blog Posts

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Ly6G Antibody - A Marker for Monocytes, Granulocytes and Neutrophils What is Ly6G?Ly6G (Lymphocyte antigen 6 complex locus G6D) is a 21-25kD glycosylphosphatidylinositol (GPI)-linked differentiation antigen that is expressed by myeloid-derived cells in a tightly developmentally-regulated manner in the bone marrow. M...    Read more.

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