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IgM Products

Antibodies
IgM Antibody (II/41) - BSA Fr ...
IgM Antibody (II/41) - BSA Free
Species: Mu
Applications: ELISA, Flow, IHC
Host: Rat Monoclonal
Formulation Catalog # Availability Price  
IgM Antibody (2123A) [Unconju ...
IgM Antibody (2123A) [Unconjugated]
MAB9435
DR555RB) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the membrane. Protocol available in COMET™ Panel Builder.​​" class="big_lightbox" target="_blank"> Multiplex Immunofluorescence IgM Antibody (2123A) [Unconjugated]
DR555RB) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the membrane. Protocol available in COMET™ Panel Builder." class="big_lightbox" target="_blank"> Multiplex Immunofluorescence IgM Antibody (2123A) [Unconjugated]
DR555RB) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the membrane. Protocol available in COMET™ Panel Builder.​" class="big_lightbox" target="_blank"> Multiplex Immunofluorescence IgM Antibody (2123A) [Unconjugated]
HAF008). A specific band was detected for IgM at approximately 65 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot IgM Antibody (2123A) [Unconjugated]
DY990). Rabbit Anti-Human IgM Monoclonal Antibody (MAB94351) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (DY998) followed by Substrate Solution (DY999) and stopping the enzymatic reaction with Stop Solution (DY994)." class="big_lightbox" target="_blank"> ELISA IgM Antibody (2123A) [Unconjugated]
HAF008) or the Anti-Rabbit IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC003). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # VCTS021). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to the membrane of B cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry IgM Antibody (2123A) [Unconjugated]
Species: Hu
Applications: WB, Simple Western, ELISA, IHC, COMET, mIF
Host: Rabbit Monoclonal
ELISA Kits
Human IgM ELISA Kit (Colorime ...
Human IgM ELISA Kit (Colorimetric)
NBP2-60477
Species: Hu
Applications: ELISA
Mouse IgM ELISA Kit (Colorime ...
Mouse IgM ELISA Kit (Colorimetric)
NBP2-61294
Species: Mu
Applications: ELISA
Bovine IgM ELISA Kit (Colorim ...
Bovine IgM ELISA Kit (Colorimetric)
NBP3-12515
Species: Bv
Applications: ELISA
Isotype Controls
Human IgM Isotype Control
Human IgM Isotype Control
DDXCH05P-100
Species: Hu
Applications: Flow, IHC, ICC/IF
Host: Human Polyclonal
Monkey IgM Isotype Control
Monkey IgM Isotype Control
NBP1-97060
Species: Pm
Applications: WB, ELISA, IHC, PAGE
Host: Monkey
Human IgM Isotype Control [Bi ...
Human IgM Isotype Control [Biotin]
NBP1-96989
Species: Hu
Applications: WB, ELISA, IP
Host: Human
Proteins
Recombinant Human IgM GST (N- ...
Recombinant Human IgM GST (N-Term)...
H00003507-P01
Species: Hu
Applications: WB, ELISA, Endotoxin, PAGE, AP
Secondary Antibodies
Goat anti-Mouse IgM Secondary ...
Goat anti-Mouse IgM Secondary Anti...
G-106-C-ABS
Species: Mu
Applications: Secondary
Host: Goat Polyclonal
Formulation Catalog # Availability Price  

Description

IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to its large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to its high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. IgM measurement yields information about the body's immediate resistance and response to infection as well as information related to specific diseases. Decreased levels are associated with immune deficiency states, hereditary deficiencies, and myeloma. Increased levels can be associated with Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease.

Bioinformatics

Entrez Human
Uniprot Human
Mouse
Product By Gene ID 3507
Alternate Names
  • AGM1
  • DKFZp686I15196
  • DKFZp686I15212
  • FLJ00385
  • immunoglobulin heavy constant mu
  • MGC104996
  • MGC52291
  • MU
  • VH

Research Areas for IgM

Find related products by research area and learn more about each of the different research areas below.

Immunology

Related IgM Blog Posts

Check out the latest blog posts on IgM.
Understanding the Importance of Human IgG
Human IgG is a component of the immune system that protects the body from infection. It is the most abundantly found antibody isotype within the circulatory system of the human body. All antibody isotypes contain two heavy chains and two light chains ...    Read more.
How To Identify B Cell Subsets Using Flow Cytometry
By Victoria OsinskiUsing Flow Cytometry to Identify B Cell SubsetsIdentifying cellular subsets by flow cytometry requires careful and thorough planning in order to ensure the correct subset of cells are identified...    Read more.

    Read more.
Early T cell response is associated with mild COVID-19 and rapid SARS-CoV-2 clearance
Jamshed Arslan, Pharm D, PhD SARS-CoV-2 induces both humoral and cellular immunity. A vaccine or natural infection invokes SARS-CoV-2-specific humoral components (antibodies from activated B cells) and cellular resp...    Read more.
Read more IgM related blogs.