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Products Related to Gene-ID: 2261

66 Results for "2261"
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MAB7662

FGFR3 Antibody (136312) [Unconjugated] - (IIIc)

(1 Review)
(3 Publications)
100 μg
MAB7662
HepG2 human hepatocellular carcinoma cell line was stained with Mouse Anti-Human FGFR3 (IIIc) Monoclonal Antibody (Catalog # MAB7662, filled histogram) or isotype control antibody (MAB002, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab')2Secondary Antibody (F0101B). Staining was performed using our Staining Membrane-associated Proteins protocol.
Hu
Species Glossary
Reactivity: Hu
WB, Flow, IHC, ICC/IF
Applications: WB, Flow, IHC, ICC/IF
Mouse Monoclonal
Host: Mouse Monoclonal
Sample Size Available
Sizes: Sample Size Available
Unconjugated  
Available Conjugates:
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 FAB7662U-100UG
Alexa Fluor 405 FAB7662V-100UG
Alexa Fluor 488 FAB7662G-100UG
Alexa Fluor 532 FAB7662X-100UG
Alexa Fluor 594 FAB7662T-100UG
Alexa Fluor 647 FAB7662R-100UG
Alexa Fluor 700 FAB7662N-100UG
Alexa Fluor 750 FAB7662S-100UG
Allophycocyanin FAB7662A
Biotin FAB7662B
CoraFluor 1 FAB7662CL1
DyLight 350 FAB7662D
DyLight 405 FAB7662E
DyLight 488 FAB7662K
DyLight 550 FAB7662L
DyLight 594 FAB7662M
DyLight 650 FAB7662W
DyLight 680 FAB7662Y
DyLight 755 FAB7662Z
FITC FAB7662F
HRP FAB7662H
Janelia Fluor 525 FAB7662JF525
Janelia Fluor 549 FAB7662I
Janelia Fluor 646 FAB7662J
Janelia Fluor 669 FAB7662JF669
PE FAB7662P
PerCP FAB7662C
mFluor Violet 450 SE FAB7662MFV450
mFluor Violet 500 SE FAB7662MFV500
mFluor Violet 610 SE FAB7662MFV610
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free MAB7662-SP
Carrier Free MAB7662-500
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MAB766

FGFR3 Antibody (136334) [Unconjugated]

(1 Review)
(4 Publications)
100 μg
MAB766
TAB cells modulate melanoma cells to express FGFR-3 and its ligand FGF-2 for tumor stroma-tumor cell cross-talk. a WM3749 co-cultured (72 h) with TAB cells (red bar) show increased FGFR-3 mRNA expression when compared with tumors only (open bar) or co-cultured with NB cells (blue bar). b Lysates obtained from pools of melanomas co-cultured (72–120 h) with NB- or TAB cells were probed in western blot with anti-FGFR-3 antibody (left panel), results expressed as relative intensity after beta -actin normalization (right panel). c Melanoma cells co-cultured with TAB cells (72 h) show increased phospho-FGFR-3 expression (right panel; immunofluorescence assays) when compared with melanoma cells alone (left panel) or melanoma cells co-cultured with NB cells (middle panel), scale bars: 40 μm, images captured by Nikon inverted microscope. d Melanoma cells co-cultured with TAB cells (red bar) show increased FGF-2 mRNA expression when compared with melanoma cells alone (open bar) or melanoma cells co-cultured with NB cells (blue bar). e 451Lu and WM989treated with IGF-1 (25 ng/ml/daily for 5 days; red bar) show increased FGFR-3 expression when compared with untreated controls (blue bar), flow cytometry results expressed as net % expression of control antibody. IGF-1 treated melanoma cells (red bars) show higher expression of FGFR-3 compared with untreated cells (blue bars). Bar represents mean + SD of replicate samples. f NB cells treated with FGF-2 (10 ng/ml/daily for 4 days; red bar) show high IGF-1 mRNA expression relative to untreated NB cells (blue bar). g 451Lu and WM989 co-cultured (72 h) with TAB cells in the presence of an anti-IGF-1 neutralizing antibody (10 μg/ml) show decreased FGFR-3 mRNA expression in tumor cells (blue bar) when compared with controls (red bar). h TAB cells co-cultured (72 h) with 451Lu and WM989 in the presence of an anti-FGF-2 neutralizing antibody (1 μg/ml) show decreased IGF-1 mRNA expression in B cells (blue bar) when compared with controls (red bar).Experiments in a, d and f–h were performed using qPCR. In Figures a, d–h, bars represent mean + SE of duplicate samples and are representative of at least two independent experiments. i Summary of cross-talk between melanoma and B cells: FGF-2 is constitutively expressed by tumor cells, released into the microenvironment to bind FGFR-3 on the B cells, activated B cells express increased levels of pro-inflammatory cytokines. IGF-1 released by TAB cells modulates tumor cells to increase their growth, heterogeneity and therapy resistance Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/28928360), licensed under a CC-BY license. Not internally tested by R&D Systems.
Hu
Species Glossary
Reactivity: Hu
WB, Flow, CyTOF-ready
Applications: WB, Flow, CyTOF-ready
Mouse Monoclonal
Host: Mouse Monoclonal
Sample Size Available
Sizes: Sample Size Available
Unconjugated  
Available Conjugates:
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 FAB766U-100UG
Alexa Fluor 405 FAB766V-100UG
Alexa Fluor 488 FAB766G-100UG
Alexa Fluor 532 FAB766X
Alexa Fluor 594 FAB766T-100UG
Alexa Fluor 647 FAB766R-100UG
Alexa Fluor 700 FAB766N-100UG
Alexa Fluor 750 FAB766S-100UG
Allophycocyanin FAB766A
Allophycocyanin/Cy7 FAB766APCCY7
Biotin FAB766B
CoraFluor 1 FAB766CL1
DyLight 350 FAB766D
DyLight 405 FAB766E
DyLight 488 FAB766K
DyLight 550 FAB766L
DyLight 594 FAB766M
DyLight 650 FAB766W
DyLight 680 FAB766Y
DyLight 755 FAB766Z
Fluorescein FAB766F
HRP FAB766H
Janelia Fluor 525 FAB766JF525
Janelia Fluor 549 FAB766I
Janelia Fluor 646 FAB766J
Janelia Fluor 669 FAB766JF669
PE/Atto594 FAB766PEATT594
PE/Cy5.5 FAB766PECY55
PE/Cy7 FAB766PECY7
Phycoerythrin FAB766P
mFluor Violet 450 SE FAB766MFV450
mFluor Violet 500 SE FAB766MFV500
mFluor Violet 610 SE FAB766MFV610
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free FAB766F
Carrier Free FAB766P
Carrier Free FAB766A
Carrier Free MAB766-SP
Carrier Free MAB766-500
Carrier Free FAB766V-100UG
Carrier Free FAB766U-100UG
Carrier Free FAB766T-100UG
Carrier Free FAB766S-100UG
Carrier Free FAB766R-100UG
Carrier Free FAB766N-100UG
Carrier Free FAB766G-100UG
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MAB7661

FGFR3 Antibody (136318) [Unconjugated]

(1 Review)
(4 Publications)
100 μg
MAB7661
Recombinant Human FGF R3 (IIIc) Fc Chimera (Catalog # 766-FR) inhibits Recombinant Human FGF acidic (Catalog # 232-FA) induced proliferation in the NR6R‑3T3 mouse fibroblast cell line in a dose-dependent manner (orange line) as measured by Resazurin (Catalog # AR002) . Inhibition of Recombinant Human FGF acidic (0.3 ng/mL) activity elicited by Recombinant Human FGF R3 (IIIc) Fc Chimera (6 ng/mL) is neutralized (green line) by increasing concentrations of Human FGF R3 Monoclonal Antibody (Catalog # MAB7661). The ND50 is typically 2.5-15 ng/mL in the presence of heparin (10 µg/mL).
Hu
Species Glossary
Reactivity: Hu
WB, B/N
Applications: WB, B/N
Mouse Monoclonal
Host: Mouse Monoclonal
Sample Size Available
Sizes: Sample Size Available
Unconjugated  
Available Conjugates:
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 FAB7661U-100UG
Alexa Fluor 405 FAB7661V-100UG
Alexa Fluor 488 FAB7661G-100UG
Alexa Fluor 532 FAB7661X-100UG
Alexa Fluor 594 FAB7661T-100UG
Alexa Fluor 647 FAB7661R-100UG
Alexa Fluor 700 FAB7661N-100UG
Alexa Fluor 750 FAB7661S-100UG
Allophycocyanin FAB7661A
Biotin FAB7661B
CoraFluor 1 FAB7661CL1
DyLight 350 FAB7661D
DyLight 405 FAB7661E
DyLight 488 FAB7661K
DyLight 550 FAB7661L
DyLight 594 FAB7661M
DyLight 650 FAB7661W
DyLight 680 FAB7661Y
DyLight 755 FAB7661Z
FITC FAB7661F
HRP FAB7661H
Janelia Fluor 525 FAB7661JF525
Janelia Fluor 549 FAB7661I
Janelia Fluor 646 FAB7661J
Janelia Fluor 669 FAB7661JF669
PE FAB7661P
PerCP FAB7661C
mFluor Violet 450 SE FAB7661MFV450
mFluor Violet 500 SE FAB7661MFV500
mFluor Violet 610 SE FAB7661MFV610
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free MAB7661-SP
Carrier Free MAB7661-500
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NBP2-66840

FGFR3 Antibody (JM110-33)

(1 Publication)
100 ul
NBP2-66840
Western Blot: FGFR3 Antibody (JM110-33) [NBP2-66840] - Analysis of FGFR3 on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:5,000 dilution was used for 1 hour at room temperature.Positive control: Lane 1: Hela cell lysateLane 2: HepG2 cell lysateLane 3: 293 cell lysateLane 4: MCF-7 cell lysate
Hu, Mu, Rt
Species Glossary
Reactivity: Hu, Mu, Rt
WB, Flow, ICC/IF, IHC
Applications: WB, Flow, ICC/IF, IHC
Rabbit Monoclonal
Host: Rabbit Monoclonal
Unconjugated  
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NBP2-52468

FGFR3 Antibody (2H10B4) - BSA Free

(2 Publications)
0.1 mg
NBP2-52468
Western Blot: FGFR3 Antibody (2H10B4) [NBP2-52468] - Analysis using FGFR3 mAb against human FGFR3 (AA: 529-694) recombinant protein. (Expected MW is 44.1 kDa)
Hu
Species Glossary
Reactivity: Hu
WB, ELISA, Flow, IHC, CyTOF-ready
Applications: WB, ELISA, Flow, IHC, CyTOF-ready
Mouse Monoclonal
Host: Mouse Monoclonal
Sample Size Available
Sizes: Sample Size Available
Unconjugated  
Available Formulations
Formulation Catalog # Availability Price  
BSA Free NBP2-52468-0.025mg
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MAB710

FGFR3 Antibody (136812)

(4 Publications)
500 μg
MAB710
Recombinant Mouse FGF R3 (IIIc) Fc Chimera (Catalog # 710-MF) inhibits Recom­binant Human FGF acidic (Catalog # 232‑FA) induced proliferation in the NR6R‑3T3 mouse fibroblast cell line in a dose-dependent manner (orange line). Inhibition of Recom­binant Human FGF acidic (0.3 ng/mL) activity elicited by Recom­binant Mouse FGF R3 (IIIc) Fc Chimera (12 ng/mL) is neutralized (green line) by increasing concentrations of Rat Anti-Mouse FGF R3 Mono­clonal Antibody (Catalog # MAB710). The ND50 is typically 3-12 µg/mL in the presence of heparin (10 µg/mL).
Mu
Species Glossary
Reactivity: Mu
B/N
Applications: B/N
Rat Monoclonal
Host: Rat Monoclonal
Sample Size Available
Sizes: Sample Size Available
Unconjugated  
Available Conjugates:
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 FAB710U-100UG
Alexa Fluor 405 FAB710V-100UG
Alexa Fluor 488 FAB710G-100UG
Alexa Fluor 532 FAB710X-100UG
Alexa Fluor 594 FAB710T-100UG
Alexa Fluor 647 FAB710R-100UG
Alexa Fluor 700 FAB710N-100UG
Alexa Fluor 750 FAB710S-100UG
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free MAB710-SP
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766-FR

Recombinant Human FGFR3 (IIIc) Fc Chimera Protein, CF

(5 Publications)
50 μg
Hu
Species Glossary
Reactivity: Hu
Bioactivity
Applications: Bioactivity
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710-MF

Recombinant Mouse FGFR3 (IIIc) Fc Chimera Protein, CF

(4 Publications)
50 μg
Mu
Species Glossary
Reactivity: Mu
Bioactivity
Applications: Bioactivity
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NBP2-45716

FGFR3 Antibody (OTI1B10)

0.1 ml
NBP2-45716
Western Blot: FGFR3 Antibody (OTI1B10) [NBP2-45716] - Equivalent amounts of cell lysates (10 ug per lane) of wild-type 293T cells and FGFR3-Knockout 293T cells were separated by SDS-PAGE and immunoblotted with anti-FGFR3 monoclonal antibody TA801078. Then the blotted membrane was stripped and reprobed with anti-b-actin antibody as a loading control (1:500).
Hu, Mu, Rt
Species Glossary
Reactivity: Hu, Mu, Rt
WB, ICC/IF, IHC, KO
Applications: WB, ICC/IF, IHC, KO
Mouse Monoclonal
Host: Mouse Monoclonal
Unconjugated  
Available Conjugates:
         
Validated by:          
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 NBP2-70722AF350
Alexa Fluor 405 NBP2-70722AF405
Alexa Fluor 488 NBP2-70722AF488
Alexa Fluor 532 NBP2-70722AF532
Alexa Fluor 594 NBP2-70722AF594
Alexa Fluor 647 NBP2-70722AF647
Alexa Fluor 700 NBP2-70722AF700
Alexa Fluor 750 NBP2-70722AF750
Allophycocyanin NBP2-70722APC
Biotin NBP2-70722B
CoraFluor 1 NBP2-70722CL1
DyLight 350 NBP2-70722UV
DyLight 405 NBP2-70722V
DyLight 488 NBP2-70722G
DyLight 550 NBP2-70722R
DyLight 594 NBP2-70722DL594
DyLight 650 NBP2-70722C
DyLight 680 NBP2-70722FR
DyLight 755 NBP2-70722IR
FITC NBP2-70722F
HRP NBP2-70722H
Janelia Fluor 525 NBP2-70722JF525
Janelia Fluor 549 NBP2-70722JF549
Janelia Fluor 646 NBP2-70722JF646
Janelia Fluor 669 NBP2-70722JF669
PE NBP2-70722PE
PerCP NBP2-70722PCP
mFluor Violet 450 SE NBP2-70722MFV450
mFluor Violet 500 SE NBP2-70722MFV500
mFluor Violet 610 SE NBP2-70722MFV610
Available Formulations
Formulation Catalog # Availability Price  
Azide and BSA Free NBP2-70722
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NBP2-41227

FGFR3 Antibody - BSA Free

0.1 mg
NBP2-41227
Western Blot: FGFR3 Antibody [NBP2-41227] - SK-N-SH cell lysate with FGFR3 antibody at (A) 0.5 and (B) 1 ug/mL.
Hu, Mu, Rt, Ch
Species Glossary
Reactivity: Hu, Mu, Rt, Ch
WB, ELISA, ICC/IF, IHC
Applications: WB, ELISA, ICC/IF, IHC
Rabbit Polyclonal
Host: Rabbit Polyclonal
Sample Size Available
Sizes: Sample Size Available
Unconjugated  
Available Conjugates:
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 NBP2-41227AF350
Alexa Fluor 405 NBP2-41227AF405
Alexa Fluor 488 NBP2-41227AF488
Alexa Fluor 532 NBP2-41227AF532
Alexa Fluor 594 NBP2-41227AF594
Alexa Fluor 647 NBP2-41227AF647
Alexa Fluor 700 NBP2-41227AF700
Alexa Fluor 750 NBP2-41227AF750
Allophycocyanin NBP2-41227APC
Biotin NBP2-41227B
CoraFluor 1 NBP2-41227CL1
DyLight 350 NBP2-41227UV
DyLight 405 NBP2-41227V
DyLight 488 NBP2-41227G
DyLight 550 NBP2-41227R
DyLight 594 NBP2-41227DL594
DyLight 650 NBP2-41227C
DyLight 680 NBP2-41227FR
DyLight 755 NBP2-41227IR
FITC NBP2-41227F
HRP NBP2-41227H
Janelia Fluor 525 NBP2-41227JF525
Janelia Fluor 549 NBP2-41227JF549
Janelia Fluor 646 NBP2-41227JF646
Janelia Fluor 669 NBP2-41227JF669
PE NBP2-41227PE
PerCP NBP2-41227PCP
mFluor Violet 450 SE NBP2-41227MFV450
mFluor Violet 500 SE NBP2-41227MFV500
mFluor Violet 610 SE NBP2-41227MFV610
Available Formulations
Formulation Catalog # Availability Price  
BSA Free NBP2-41227-0.025mg
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DYC766-2

Human Total FGFR3 DuoSet IC ELISA, 2 Plate

(1 Publication)
1 Kit (for 2 Plates)
DYC766-2
ELISA FGFR3 [Biotin]
Hu
Species Glossary
Reactivity: Hu
ELISA
Applications: ELISA
Conjugate Catalog # Availability Size Price
Biotin DYC766-5
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1264-FR

Recombinant Human FGFR3 (IIIb) Fc Chimera Protein, CF

(2 Publications)
50 μg
Hu
Species Glossary
Reactivity: Hu
Bioactivity
Applications: Bioactivity
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free 1264-FR-01M
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