Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IP, MS, KD, KO
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB, Simple Western, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
Factor Inhibiting HIF1 (FIH) protein facilitates repression of HIF-1 transcriptional activity by binding to VHL, which acts as a transcriptional corepressor. VHL inhibits HIF-1 alpha transactivation function by recruiting histone deacetylases. Involvement of VHL in association with FIH provides a unifying mechanism for the modulation of HIF-1 alpha protein stabilization and transcriptional activation in response to changes in cellular oxygen concentration.
Bioinformatics
| Entrez |
Rat
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
55662 |
| Alternate Names |
- DKFZp762F1811
- EC 1.14.11.16
- factor inhibiting HIF1
- Factor inhibiting HIF-1
- FIH1FIH-1
- FLJ20615
- FLJ22027
- hypoxia inducible factor 1, alpha subunit inhibitor
- hypoxia-inducible factor 1-alpha inhibitor
- Hypoxia-inducible factor asparagine hydroxylase
- peptide-aspartate beta-dioxygenase
|
![Western Blot FIH-1/HIF-1AN Antibody (745122) [Unconjugated]](http://images.novusbio.com/fullsize2/FIH1_MAB7874_Western_Blot_12842.jpg)
![Immunocytochemistry FIH-1/HIF-1AN Antibody (745122) [Unconjugated]](http://images.novusbio.com/fullsize2/FIH1_MAB7874_Immunocytochemistry__Immunofluorescence_22066.jpg)
![Simple Western FIH-1/HIF-1AN Antibody (745122) [Unconjugated]](http://images.novusbio.com/fullsize2/16384.jpg)
![Immunocytochemistry FIH-1/HIF-1AN Antibody (745122) [Unconjugated]](http://images.novusbio.com/fullsize2/mab7874_human-mouse-fih-1-hif-1an-mab-clone-745122-immunocytochemistry-84202215150.jpg)
