After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.
HAF018). A specific band was detected for FIH-1/HIF-1AN at approximately 42 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
NL007) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm and nuclei. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank">
NL007) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. Staining was performed using our protocol for Fluorescent ICC Staining of Non-adherent Cells." class="big_lightbox" target="_blank">
Factor Inhibiting HIF1 (FIH) protein facilitates repression of HIF-1 transcriptional activity by binding to VHL, which acts as a transcriptional corepressor. VHL inhibits HIF-1 alpha transactivation function by recruiting histone deacetylases. Involvement of VHL in association with FIH provides a unifying mechanism for the modulation of HIF-1 alpha protein stabilization and transcriptional activation in response to changes in cellular oxygen concentration.
![Western Blot FIH-1/HIF-1AN Antibody (745122) [Unconjugated]](http://images.novusbio.com/images/antibody/FIH1_MAB7874_Western_Blot_12842.jpg)
![Immunocytochemistry FIH-1/HIF-1AN Antibody (745122) [Unconjugated]](http://images.novusbio.com/images/antibody/FIH1_MAB7874_Immunocytochemistry__Immunofluorescence_22066.jpg)
![Simple Western FIH-1/HIF-1AN Antibody (745122) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/16384.jpg)
![Immunocytochemistry FIH-1/HIF-1AN Antibody (745122) [Unconjugated]](http://images.novusbio.com/images/antibody/mab7874_human-mouse-fih-1-hif-1an-mab-clone-745122-immunocytochemistry-84202215150.jpg)
