Species: Hu, Mu
Applications: WB, ELISA, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Mu
Applications: WB, IHC
Host: Goat Polyclonal
Species: Hu, Mu
Applications: WB, ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Mu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Description
Wnt1 is a secreted protein that signals through the Frizzled family of cell surface receptors and is required for normal embryonic development. Wnt1 activation induces a complex signaling cascade that ultimately leads to the increased expression of over fifty genes. An important component of Wnt1 signaling is the stabilization, and resulting accumulation, of the intracellular signaling protein, beta catenine. Mature human Wnt1 is a glycosylated protein containing 343 amino acid residues. Elevated levels of Wnt proteins are associated with tumorigenesis and are present in numerous human breast cancers.
Bioinformatics
| Entrez |
Human
Mouse
|
| Uniprot |
Human
|
| Product By Gene ID |
7471 |
| Alternate Names |
- Int-1
- INT1Proto-oncogene Int-1 homolog
- proto-oncogene Wnt-1
- wingless-type MMTV integration site family, member 1 (oncogene INT1)
- wingless-type MMTV integration site family, member 1
- Wnt1
- Wnt-1
|
![Bioactivity Wnt-1 [Unconjugated]](http://images.novusbio.com/fullsize2/Wnt1_9765WN_2784.jpg)
![Bioactivity Wnt-1 [Unconjugated]](http://images.novusbio.com/fullsize2/11160-wn_recombinant-human-wnt-1-sfrp-1-complex-protein-cf-bioactivity-245202212232.jpg)
