Wnt proteins are a family of cysteine rich glycoproteins that play a role in embryonic development and cellular homeostasis, but have also been shown to play a role in the development of certain cancers and other pathological conditions. The Wnt signaling pathway contains three branches: the Canonical (beta-catenin) pathway, the planar cell polarity pathway and the Wnt/Ca2+ pathway. This pathway consists of a set of short-range, secreted signaling molecules that bind to specific receptors to activate complex signaling cascades. Key players in Wnt signaling include beta Catenin, Dishevelled, GSK3 beta, APC and Frizzled receptors.
All Wnt Signaling Pathway Antibodies, Lysates, Proteins, and RNAi