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VE-Cadherin Products

Antibodies
VE-Cadherin Antibody [Unconju ...
VE-Cadherin Antibody [Unconjugated]
AF1002
HAF017). A specific band was detected for VE‑Cadherin at approximately 120 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot VE-Cadherin Antibody [Unconjugated]
VC004). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell membranes. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_lightbox" target="_blank"> Immunohistochemistry VE-Cadherin Antibody [Unconjugated]
AF1002) at 3ug/mL with 1 hour incubation at room temperature followed by incubation with anti-goat IgG VisUCyte HRP Polymer Antibody (Catalog # VC004) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue). Specific staining was localized to cardiac myocytes. " class="big_lightbox" target="_blank"> In-situ Hybridization VE-Cadherin Antibody [Unconjugated]
Species: Mu
Applications: WB, Simple Western, IHC, Dual ISH-IHC
Host: Goat Polyclonal
VE-Cadherin Antibody [Unconju ...
VE-Cadherin Antibody [Unconjugated]
AF938
HAF017). A specific band was detected for VE-Cadherin at approximately 125 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot VE-Cadherin Antibody [Unconjugated]
NL001) and counterstained with DAPI (blue). Specific staining was localized to the plasma membrane. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry VE-Cadherin Antibody [Unconjugated]
AB-108-C, open histogram) followed by Allophycocyanin-conjugated Anti-Goat IgG Secondary Antibody (F0108). View our protocol for Staining Membrane-associated Proteins." class="big_lightbox" target="_blank"> Flow Cytometry VE-Cadherin Antibody [Unconjugated]
Species: Hu
Applications: WB, Simple Western, Flow, CyTOF-ready, ICC/IF
Host: Goat Polyclonal
VE-Cadherin Antibody (123413) ...
VE-Cadherin Antibody (123413) [Unc...
MAB9381
HAF018). A specific band was detected for VE-Cadherin at approximately 125 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot VE-Cadherin Antibody (123413) [Unconjugated]
NL007) and counterstained with DAPI (blue). Specific staining was localized to plasma membrane. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry VE-Cadherin Antibody (123413) [Unconjugated]
MAB004, open histogram) followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (F0101B). View our protocol for Staining Membrane-associated Proteins." class="big_lightbox" target="_blank"> Flow Cytometry VE-Cadherin Antibody (123413) [Unconjugated]
Species: Hu
Applications: WB, Flow, CyTOF-ready, ICC/IF
Host: Mouse Monoclonal
Antibody Pairs
VE-Cadherin Antibody Pair [HR ...
VE-Cadherin Antibody Pair [HRP]
NBP2-79463
Species: Hu
Applications: ELISA
Host: Monoclonal
Conjugate Catalog # Availability Size Price
ELISA Kits
Human VE-Cadherin Quantikine ...
Human VE-Cadherin Quantikine ELISA...
DCADV0
Species: Hu
Applications: ELISA
Mouse VE-Cadherin ELISA Kit ( ...
Mouse VE-Cadherin ELISA Kit (Color...
NBP3-20089
Species: Mu
Applications: ELISA
Human VE-Cadherin DuoSet ELIS ...
Human VE-Cadherin DuoSet ELISA, 5 ...
DY938-05
Species: Hu
Applications: ELISA
Proteins
Recombinant Human VE-Cadherin ...
Recombinant Human VE-Cadherin Fc C...
938-VC
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Mouse VE-Cadherin ...
Recombinant Mouse VE-Cadherin Fc C...
1002-VC
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human VE-Cadherin ...
Recombinant Human VE-Cadherin Prot...
8440-VC
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  

Description

VE-cadherin (cadherin-5) is an endothelial specific adhesion molecule that is essential for the maintenance of endothelial barrier function and angiogenesis. VE-cadherin is linked to the actin cytoskeleton through a number of adaptor proteins including a-, â-, and ã-catenin. Cytoskeletal dynamics and phosphorylation regulate VE-cadherin mediated cell-cell adhesion. The cytosolic C-terminal Src kinase (Csk) binds via its SH2 domain to the phosphorylated tyrosine 658 site of VE-cadherin. This interaction regulates density dependent cell proliferation. Phosphorylation of tyrosine 658 has also been shown to lead to the uncoupling of p120-catenin from the cytoplasmic tail of VE-cadherin. This phosphorylation event is sufficient to maintain cells in a mesenchymal state during the cell invasion phase of angiogenesis.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Mouse
Product By Gene ID 1003
Alternate Names
  • 7B4 antigen
  • 7B4
  • cadherin 5, type 2 (vascular endothelium)
  • cadherin 5, type 2, VE-cadherin (vascular epithelium)
  • cadherin-5
  • CD144 antigen
  • CD144
  • endothelial-specific cadherin
  • FLJ17376
  • Vascular endothelial cadherin
  • VE-cadherin

Research Areas for VE-Cadherin

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication
Cellular Markers
Extracellular Matrix
Phospho-Specific
Plasma Membrane Markers
Signal Transduction

Related VE-Cadherin Blog Posts

Check out the latest blog posts on VE-Cadherin.

    Read more.
Read more VE-Cadherin related blogs.