VE-Cadherin Products

Antibodies
VE-Cadherin Antibody [Unconju ...
VE-Cadherin Antibody [Unconjugated]
AF1002
Species: Mu
Applications: WB
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
VE-Cadherin [p Tyr731] Antibo ...
VE-Cadherin [p Tyr731] Antibody
NBP1-51393
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
VE-Cadherin Antibody [Unconju ...
VE-Cadherin Antibody [Unconjugated]
AF938
Species: Hu
Applications: WB, Flow, ICC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
ELISA Kits
VE-Cadherin ELISA Kit [Biotin ...
VE-Cadherin ELISA Kit [Biotin]
KA0271
Species: Pm
VE-Cadherin ELISA Kit
VE-Cadherin ELISA Kit
NBP1-91254
Proteins
VE-Cadherin Recombinant Prote ...
VE-Cadherin Recombinant Protein
NBP2-52210
Species: Mu
Applications: PAGE
RNAi
VE-Cadherin RNAi
VE-Cadherin RNAi
H00001003-R01
Species: Hu

Description

VE-cadherin (cadherin-5) is an endothelial specific adhesion molecule that is essential for the maintenance of endothelial barrier function and angiogenesis. VE-cadherin is linked to the actin cytoskeleton through a number of adaptor proteins including a-, â-, and ã-catenin. Cytoskeletal dynamics and phosphorylation regulate VE-cadherin mediated cell-cell adhesion. The cytosolic C-terminal Src kinase (Csk) binds via its SH2 domain to the phosphorylated tyrosine 658 site of VE-cadherin. This interaction regulates density dependent cell proliferation. Phosphorylation of tyrosine 658 has also been shown to lead to the uncoupling of p120-catenin from the cytoplasmic tail of VE-cadherin. This phosphorylation event is sufficient to maintain cells in a mesenchymal state during the cell invasion phase of angiogenesis.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Mouse
Product By Gene ID 1003
Alternate Names
  • Vascular endothelial cadherin
  • endothelial-specific cadherin
  • CD144 antigen
  • cadherin-5
  • cadherin 5, type 2, VE-cadherin (vascular epithelium)
  • FLJ17376
  • CD144
  • VE-cadherin
  • 7B4
  • 7B4 antigen
  • cadherin 5, type 2 (vascular endothelium)

Research Areas for VE-Cadherin

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication
Cellular Markers
Extracellular Matrix
Phospho-Specific
Plasma Membrane Markers
Signal Transduction

PTMs for VE-Cadherin

Learn more about PTMs related to VE-Cadherin.

Methylation
Phosphorylation

Bioinformatics Tool for VE-Cadherin

Discover related pathways, diseases and genes to VE-Cadherin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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