ULBP-1 Products

Antibodies
ULBP-1 Antibody [Unconjugated ...
ULBP-1 Antibody [Unconjugated]
AF1380
Species: Hu
Applications: WB, Block
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Proteins
ULBP-1 Recombinant Protein An ...
ULBP-1 Recombinant Protein Antigen
NBP1-80856PEP
Species: Hu
Applications: AC
ULBP-1 Recombinant Protein
ULBP-1 Recombinant Protein
NBP2-53076
Species: Hu
Applications: PAGE
ULBP-1 Recombinant Protein
ULBP-1 Recombinant Protein
NBP2-22930
Species: Hu
Applications: PAGE
RNAi
ULBP-1 RNAi
ULBP-1 RNAi
H00080329-R02
Species: Hu

Description

Ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signalingpathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands toNKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transductionpathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked theinteraction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system.UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 80329
Alternate Names
  • UL16-binding protein 1
  • N2DL1
  • NKG2DL1
  • ALCAN-beta
  • N2DL-1
  • NKG2D ligand 1
  • Retinoic acid early transcript 1I
  • RAET1Ialcan-beta
  • UL16 binding protein 1

PTMs for ULBP-1

Learn more about PTMs related to ULBP-1.

Cleavage
Phosphorylation
Glycosylation
Gpi Anchoring

Bioinformatics Tool for ULBP-1

Discover related pathways, diseases and genes to ULBP-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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