TGF-beta 2 Products

Antibodies
TGF-beta 2 Antibody (8607) [U ...
TGF-beta 2 Antibody (8607) [Unconj...
MAB612
Species: Multi
Applications: WB, IHC, ELISA(Cap)
Host: Mouse Monoclonal
TGF-beta 2 Antibody [Unconjug ...
TGF-beta 2 Antibody [Unconjugated]
AB-12-NA
Species: Multi
Applications: WB, Simple Western, Neut
Host: Rabbit Polyclonal
TGF-beta 2 Antibody
TGF-beta 2 Antibody
NBP2-31079
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
ELISA Kits
TGF-beta 2 ELISA Kit
TGF-beta 2 ELISA Kit
NBP1-91255
Species: Hu
Applications: ELISA
Lysates
TGF-beta 2 Overexpression Lys ...
TGF-beta 2 Overexpression Lysate (...
NBL1-16854
Applications: WB
TGF-beta 2 Overexpression Lys ...
TGF-beta 2 Overexpression Lysate (...
H00007042-T01
Applications: WB
Proteins
Human TGF-beta 2 Biologically ...
Human TGF-beta 2 Biologically Acti...
NBP2-36433
Species: Hu
Applications: Func, PAGE
TGF-beta 2 Recombinant Protei ...
TGF-beta 2 Recombinant Protein
H00007042-P01
Species: Hu
Applications: WB, ELISA, PA
TGF-beta 2 Recombinant Protei ...
TGF-beta 2 Recombinant Protein
NBP1-99913
Species: Hu

Description

Transforming Growth Factor (TGF) betas mediate many cell to cell interactions that occur during embryonic development. Three TGF betas have been identified in mammals. TGF beta 1, TGF beta 2 and TGF beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide. TGF beta 1, TGF beta 2, and TGF beta 1.2 appear to be equivalent in biological activity, although there does appear to be differences in binding to certain types of receptors. TGF beta 2 is produced by many cell types and has been found in the highest concentration in porcine platelets and mammalian bone. Latent TGF beta 2 is the prominent isoform found in body fluids such as amniotic fluid, breast milk, and the aqueous and vitreous humor of the eye.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 7042
Alternate Names
  • Polyergin
  • MGC116892
  • Cetermin
  • BSC-1 cell growth inhibitor
  • transforming growth factor beta-2
  • TGF-beta-2
  • polyergin
  • G-TSF
  • cetermin
  • Glioblastoma-derived T-cell suppressor factor
  • TGF-beta2
  • transforming growth factor, beta 2

Research Areas for TGF-beta 2

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Apoptosis
Biologically Active Proteins
Cell Cycle and Replication

Bioinformatics Tool for TGF-beta 2

Discover related pathways, diseases and genes to TGF-beta 2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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