TCF7L2 Products

Antibodies
TCF7L2 Antibody (3A4)
TCF7L2 Antibody (3A4)
H00006934-M06
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
TCF7L2 Antibody (6F12-3)
TCF7L2 Antibody (6F12-3)
NB110-10889
Species: Hu, Mu
Applications: WB, IHC, IHC-Fr, IHC-P
Host: Mouse Monoclonal
Lysates
TCF7L2 Overexpression Lysate ...
TCF7L2 Overexpression Lysate (Native)
NBL1-16777
Applications: WB
TCF7L2 Overexpression Lysate ...
TCF7L2 Overexpression Lysate (Native)
NBP2-10147
Applications: WB
TCF7L2 Overexpression Lysate ...
TCF7L2 Overexpression Lysate (Native)
NBP2-10154
Applications: WB
Proteins
TCF7L2 Peptide
TCF7L2 Peptide
NBP1-19083PEP
Species: Hu
Applications: WB, PEP-ELISA
TCF7L2 Recombinant Protein
TCF7L2 Recombinant Protein
H00006934-P01
Species: Hu
Applications: WB, ELISA, PA
TCF7L2 Partial Recombinant Pr ...
TCF7L2 Partial Recombinant Protein
H00006934-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
TCF7L2 RNAi
TCF7L2 RNAi
H00006934-R01V
Species: Hu
Applications: WB, RNAi SP
TCF7L2 RNAi
TCF7L2 RNAi
H00006934-R01
Species: Hu

Description

TCF7L2, or TCF4, is a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. TCF7L2 has been implicated in glucose homeostasis through the regulation of pro-glucagon gene expression, which encodes glucagon-like peptide 1 (GLP-1). Genetic variants of TCF7L2 have been linked to type 2 diabetes, and it has specifically been shown to have an important role in the regulation of both 946;-cell survival and function (4). Several splicing isoforms for TCF7L2 have been shown to be differentially expressed in tissues during cancer progression (3), and gene targeting studies indicate that TCF7L2 is required to maintain the crypt stem cells of the small intestine (1, 2).

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 6934
Alternate Names
  • transcription factor 7-like 2
  • T-cell factor-4 variant D
  • T-cell factor-4 variant X2
  • T-cell factor-4 variant C
  • T-cell factor-4 variant M
  • T-cell factor-4 variant B
  • T-cell factor-4 variant L
  • T-cell factor-4 variant A
  • T-cell factor-4 variant K
  • T-cell-specific transcription factor 4
  • T-cell factor-4 variant J
  • T-cell factor 4
  • T-cell factor-4 variant I
  • HMG box transcription factor 4
  • T-cell factor-4 variant H
  • hTCF-4
  • TCF4T-cell factor-4 variant G
  • TCF-4T-cell factor-4 variant F
  • T-cell factor-4 variant E
  • transcription factor 7-like 2 (T-cell specific, HMG-box)

Research Areas for TCF7L2

Find related products by research area and learn more about each of the different research areas below.

Cancer
Signal Transduction
Wnt Signaling Pathway

Bioinformatics Tool for TCF7L2

Discover related pathways, diseases and genes to TCF7L2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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