TC-PTP/PTPN2 Products

Antibodies
TC-PTP/PTPN2 Antibody
TC-PTP/PTPN2 Antibody
NBP2-48841
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
TC-PTP/PTPN2 Antibody
TC-PTP/PTPN2 Antibody
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
TC-PTP/PTPN2 Antibody (252294 ...
TC-PTP/PTPN2 Antibody (252294) [Un...
MAB1930
Species: Hu, Mu, Rt
Applications: WB
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
Antibody Pairs
TC-PTP/PTPN2 Antibody Pair
TC-PTP/PTPN2 Antibody Pair
H00005771-AP22
Species: Hu
Applications: S-ELISA
Lysates
TC-PTP/PTPN2 Overexpression L ...
TC-PTP/PTPN2 Overexpression Lysate
NBL1-14972
Species: Hu
Applications: WB
TC-PTP/PTPN2 Overexpression L ...
TC-PTP/PTPN2 Overexpression Lysate
NBP2-08070
Species: Hu
Applications: WB
Proteins
Recombinant Human TC-PTP (aa ...
Recombinant Human TC-PTP (aa 2-314...
1930-PT
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
TC-PTP/PTPN2 Recombinant Prot ...
TC-PTP/PTPN2 Recombinant Protein A...
NBP2-48841PEP
Species: Hu
Applications: AC
TC-PTP/PTPN2 Recombinant Prot ...
TC-PTP/PTPN2 Recombinant Protein A...
NBP2-48528PEP
Species: Hu
Applications: AC

Description

PTPN2 is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Three alternatively spliced variants of this gene, which encode isoforms differing at their extreme C-termini, have been described. The different C-termini are thought to determine the substrate specificity, as well as the cellular localization of the isoforms. Two highly related but distinctly processed pseudogenes that localize to distinct chromosomes have been reported. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 5771
Alternate Names
  • tyrosine-protein phosphatase non-receptor type 2
  • TCELLPTP
  • T-cell protein tyrosine phosphatase
  • TC-PTP
  • PTPTPTN2
  • TCPTPEC 3.1.3.48
  • T-cell protein-tyrosine phosphatase
  • protein tyrosine phosphatase, non-receptor type 2

PTMs for TC-PTP/PTPN2

Learn more about PTMs related to TC-PTP/PTPN2.

Phosphorylation
Dephosphorylation
Oxidation
Methylation

Bioinformatics Tool for TC-PTP/PTPN2

Discover related pathways, diseases and genes to TC-PTP/PTPN2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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