Smoothened Products

Antibodies
Smoothened Antibody
Smoothened Antibody
NBP2-24543
Species: Hu, Mu, Pm
Applications: WB, IHC-P
Host: Rabbit Polyclonal
Smoothened Antibody
Smoothened Antibody
NB100-55392
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Smoothened Antibody
Smoothened Antibody
NB100-55397
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Lysates
Smoothened Overexpression Lys ...
Smoothened Overexpression Lysate (...
NBP2-10451
Applications: WB
Proteins
Smoothened Partial Recombinan ...
Smoothened Partial Recombinant Pro...
H00006608-Q01
Species: Hu
Applications: WB, ELISA, PA
Smoothened Partial Recombinan ...
Smoothened Partial Recombinant Pro...
H00006608-Q02
Species: Hu
Applications: WB, ELISA, PA
Smoothened Recombinant Protei ...
Smoothened Recombinant Protein
H00006608-Q03
Species: Hu
Applications: WB, ELISA, PA
RNAi
Smoothened RNAi
Smoothened RNAi
H00006608-R02
Species: Hu

Description

Smoothened, a Frizzled Receptor, is homologous to the Drosophila segment polarity Smo gene. It associates with the Patched protein to mediate the cellular response to the Hedgehog secreted protein signal, which controls patterning and growth during vertebrate development. Smoothened is activated in a number of human tumors and can function as an oncogene in basal-cell carcinomas. Smoothened expression has been documented in bladder, blood, brain, the central nervous system, skin, and ureter. ESTs have been isolated from amnion, bone, brain, breast, embryo, eye, heart, nerve, and skin libraries.

Bioinformatics

Entrez Human
Mouse
Rat
Bovine
Uniprot Human
Human
Human
Human
Product By Gene ID 6608
Alternate Names
  • smoothened (Drosophila) homolog
  • smoothened homolog
  • Protein Gx
  • SMOHseven transmembrane helix receptor
  • Gx
  • smoothened homolog (Drosophila)

Research Areas for Smoothened

Find related products by research area and learn more about each of the different research areas below.

GPCR
Growth and Development
Neuronal Cell Markers

Bioinformatics Tool for Smoothened

Discover related pathways, diseases and genes to Smoothened. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Smoothened Blog Posts

Check out the latest blog posts on Smoothened.
The role of Smoothened in pulmonary pathologies
The Hedgehog (Hh) family of secreted proteins is involved in a number of developmental processes, one of which is the development of cancer. Past data suggests that the Sonic hedgehog (Shh) receptor is composed of two transmembrane proteins, Patche...    Read more.
Pancreatic Cancer Research Targets Hedgehog Signaling Pathway
The Hedgehog Signaling Pathway (HSP) is an important pathway involved in embryonic development by regulating cell differentiation. This pathway has also become an increasingly hot topic in cancer research in recent years. The HSP involves the interact...    Read more.
Read more Smoothened related blogs.