SLC7A5/LAT1 Products


Mammalian cells have several amino acid transport systems. These systems have been defined by both activity and specific genes. L-type amino acid transporter 1 (LAT1) is a 12 membrane-spanning protein. LAT1 is a Na + -independent neutral amino acid transporter agency and essential for the transporter of large neutral amino acid such as Leucine, Isoleucine, and Valine through the plasma membrane. LAT1 has been proposed to be one of the major nutrient transport systems at the blood-brain barrier. Drugs such as L Dopa are transported by LAT1. LAT1 is thought to be up-regulated to support the high protein synthesis for cell growth in some tumor cell lines.


Entrez Human
Uniprot Human
Product By Gene ID 8140
Alternate Names
  • 4F2 LC
  • CD98LC
  • sodium-independent neutral amino acid transporter LAT1,4F2LC
  • Solute carrier family 7 member 5
  • large neutral amino acids transporter small subunit 1
  • Integral membrane protein E16
  • large neutral amino acids transporter 1
  • E16
  • y+ system cationic amino acid transporter
  • CD98
  • D16S469EL-type amino acid transporter 1
  • LAT1hLAT1
  • MPE16CD98 light chain
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 5,4F2 light chain

Research Areas for SLC7A5/LAT1

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PTMs for SLC7A5/LAT1

Learn more about PTMs related to SLC7A5/LAT1.


Bioinformatics Tool for SLC7A5/LAT1

Discover related pathways, diseases and genes to SLC7A5/LAT1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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