Hu, Mu, Ca, Bovine, Chicken, Equine, Fish, Guinea Pig, Primate, Porcine, Rabbit, Reptile, Rat, Xenopus, Zebrafish, Turkey, MonkeyApplications:
WB, ICC/IF, IHC, IHC-PHost:
Hu, Mu, Rt, Bv, PmApplications:
Species: Hu, Mu, Rt, Ch, Pm, Bovine, Equine
Host: Rabbit Polyclonal
Applications: Func, PAGE
NAMPT encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. This gene has a pseudogene on chromosome 10.
|Product By Gene ID
- EC 22.214.171.124
- Pre-B-cell colony-enhancing factor 1
- Pre-B cell-enhancing factor
- pre-B-cell colony enhancing factor 1
- nicotinamide phosphoribosyltransferase
Bioinformatics Tool for PBEF/Visfatin/NAMPT
Discover related pathways, diseases and genes to PBEF/Visfatin/NAMPT. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.