p27/Kip1 Products

Antibodies
p27/Kip1 [p Thr198] Antibody
p27/Kip1 [p Thr198] Antibody
AF3994
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
p27/Kip1 [p Thr157] Antibody
p27/Kip1 [p Thr157] Antibody
AF1555
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
p27/Kip1 Antibody
p27/Kip1 Antibody
Species: Hu, Mu, Monkey
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Host: Rabbit Polyclonal
Lysates
p27/Kip1 Overexpression Lysat ...
p27/Kip1 Overexpression Lysate (De...
H00001027-T01
Species: Hu
Applications: WB
p27/Kip1 Overexpression Lysat ...
p27/Kip1 Overexpression Lysate (De...
H00001027-T03
Species: Hu
Applications: WB
p27/Kip1 Overexpression Lysat ...
p27/Kip1 Overexpression Lysate (De...
H00001027-T02
Species: Hu
Applications: WB
Proteins
p27/Kip1 Recombinant Protein
p27/Kip1 Recombinant Protein
H00001027-P01
Species: Hu
Applications: WB, ELISA, PA
p27/Kip1 Partial Recombinant ...
p27/Kip1 Partial Recombinant Protein
H00001027-Q01
Species: Hu
Applications: WB, ELISA, PA
p27/Kip1 Partial Recombinant ...
p27/Kip1 Partial Recombinant Protein
H00001027-Q02
Species: Hu
Applications: WB, ELISA, PA
RNAi
p27/Kip1 RNAi
p27/Kip1 RNAi
H00001027-R01
Species: Hu

Description

p27(Kip1) is a cyclin-dependent kinase inhibitor involved in G1 arrest. p27(Kip1) binds to and inhibits cyclinE-Cdk2 complex, cyclinA-CDK2 and cyclinD1-CDK4 (1). p27(Kip1) is regulated by phosphorylation on serine 10 (S10) and threonine 187 (T187). Phosphorylation by CDK2 on T187 results in ubiquitylation and degradation of p27(Kip1) (2); while phosphorylation by hKIS on S10 signals the nuclear export to the cytoplasm (3).

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Chicken
Product By Gene ID 1027
Alternate Names
  • p27Kip1
  • MEN4
  • Cyclin-dependent kinase inhibitor p27
  • CDKN4
  • cyclin-dependent kinase inhibitor 1B
  • KIP1P27KIP1
  • MEN1B
  • cyclin-dependent kinase inhibitor 1B (p27, Kip1)

Research Areas for p27/Kip1

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Cell Cycle and Replication
DNA Repair
Phospho-Specific
Prostate Cancer
Tumor Suppressors

Bioinformatics Tool for p27/Kip1

Discover related pathways, diseases and genes to p27/Kip1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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