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p27/Kip1 Products

Antibodies
ELISA Kits
Mouse p27/Kip1 ELISA Kit (Col ...
Mouse p27/Kip1 ELISA Kit (Colorime...
NBP2-75208
Species: Mu
Applications: ELISA
Human p27/Kip1 ELISA Kit (Col ...
Human p27/Kip1 ELISA Kit (Colorime...
NBP2-66683
Species: Hu
Applications: ELISA
Human Total p27/Kip1 DuoSet I ...
Human Total p27/Kip1 DuoSet IC ELI...
DYC2256-2
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Lysates
p27/Kip1 293T Cell Transient ...
p27/Kip1 293T Cell Transient Overe...
H00001027-T02
Species: Hu
Applications: WB
Proteins
Recombinant Human p27/Kip1 Hi ...
Recombinant Human p27/Kip1 His Pro...
NBP1-72503
Species: Hu
Applications: PAGE
p27/Kip1 Recombinant Protein ...
p27/Kip1 Recombinant Protein Antigen
NBP2-56105PEP
Species: Hu
Applications: AC

Description

p27(Kip1) is a cyclin-dependent kinase inhibitor involved in G1 arrest. p27(Kip1) binds to and inhibits cyclinE-Cdk2 complex, cyclinA-CDK2 and cyclinD1-CDK4 (1). p27(Kip1) is regulated by phosphorylation on serine 10 (S10) and threonine 187 (T187). Phosphorylation by CDK2 on T187 results in ubiquitylation and degradation of p27(Kip1) (2); while phosphorylation by hKIS on S10 signals the nuclear export to the cytoplasm (3).

Bioinformatics

Product By Gene ID 1027
Alternate Names
  • CDKN1B
  • CDKN4
  • cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • cyclin-dependent kinase inhibitor 1B
  • Cyclin-dependent kinase inhibitor p27
  • Kip1
  • KIP1P27KIP1
  • MEN1B
  • MEN4
  • p27
  • p27Kip1

Research Areas for p27/Kip1

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Cell Cycle and Replication
DNA Repair
Prostate Cancer
Tumor Suppressors