Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, RM
Applications: WB, ICC/IF, IHC, IP, KO
Host: Rabbit Polyclonal
Species: Mu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
p27(Kip1) is a cyclin-dependent kinase inhibitor involved in G1 arrest. p27(Kip1) binds to and inhibits cyclinE-Cdk2 complex, cyclinA-CDK2 and cyclinD1-CDK4 (1). p27(Kip1) is regulated by phosphorylation on serine 10 (S10) and threonine 187 (T187). Phosphorylation by CDK2 on T187 results in ubiquitylation and degradation of p27(Kip1) (2); while phosphorylation by hKIS on S10 signals the nuclear export to the cytoplasm (3).
Bioinformatics
| Uniprot |
Human
Human
Human
Human
Human
Chicken
|
| Product By Gene ID |
1027 |
| Alternate Names |
- CDKN4
- cyclin-dependent kinase inhibitor 1B (p27, Kip1)
- cyclin-dependent kinase inhibitor 1B
- Cyclin-dependent kinase inhibitor p27
- KIP1P27KIP1
- MEN1B
- MEN4
- p27Kip1
|
![Western Blot p27/Kip1 [p Thr157] Antibody](http://images.novusbio.com/fullsize2/p27_AF1555_Western_Blot_5119.jpg)
![Western Blot p27/Kip1 [p Thr198] Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/p27_AF3994_Western_Blot_5374.jpg)
![ELISA p27/Kip1 [Biotin]](http://images.novusbio.com/fullsize2/dyc2256-2_human-total-p27-kip1-duoset-ic-economy-pack-15-plate-elisa-159202015556.jpg)
