Hu, Mu, RtApplications:
WB, IHC, IHC-P, IP, ICC/IFHost:
Species: Hu, Mu, Rt, Ca, Pm
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Species: Hu, Mu, Ca, Mk
Applications: WB, IHC, ICC/IF
Host: Mouse monoclonal
WB, ELISA, IP, PA, AP
Applications: RNAi, RNAi SP
Non-POU-domain-containing octamer binding protein (NONO) is a member of the DBHS (drosophila behavior, human splicing) domain-containing family and is an RNA- and DNA- binding protein. NONO and other DBHS domain-containing proteins are multifunctional and are reported to be involved in transcriptional regulation, mRNA processing, and DNA non-homologous end joining (NHEJ). NONO functions as a coregulator of the androgen receptor (AR) and also regulates cAMP transcriptional activity by interacting with gene promoter elements. NONO is also involved in pre-mRNA splicing through an interaction with U5 snRNA and can stimulate DNA nonhomologous end joining (NHEJ) through the interaction with ku70/G22p and ku80/XRCC5 dimers. Alternate names for NONO include 54 kDa nuclear RNA- and DNA-binding protein, p54 (nrb), 55 kDa nuclear protein, NMT55, DNA-binding p52/p100 complex, NRB54, P54, and P54NRB.
Bioinformatics Tool for NONO
Discover related pathways, diseases and genes to NONO. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.