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Noggin Products

Antibodies
Noggin Antibody [Unconjugated ...
Noggin Antibody [Unconjugated]
AF719
CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry Noggin Antibody [Unconjugated]
NL001) and counterstained with DAPI (blue, lower panel). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry Noggin Antibody [Unconjugated]
Species: Mu
Applications: WB, IHC, ICC/IF
Host: Goat Polyclonal
Noggin Antibody (A9) - BSA Fr ...
Noggin Antibody (A9) - BSA Free
NBP3-41765
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
ELISA Kits
Human Noggin ELISA Kit (Color ...
Human Noggin ELISA Kit (Colorimetric)
NBP2-80296
Species: Hu
Applications: ELISA
Mouse Noggin - Ready-To-Use ...
Mouse Noggin - Ready-To-Use ELISA...
NBP3-53504
Species: Mu
Applications: ELISA
Rat Noggin - Ready-To-Use EL ...
Rat Noggin - Ready-To-Use ELISA K...
NBP3-53561
Species: Rt
Applications: ELISA
Lysates
Noggin Overexpression Lysate
Noggin Overexpression Lysate
NBL1-13707
Species: Hu
Applications: WB
Proteins
Recombinant Human Noggin Prot ...
Recombinant Human Noggin Protein
6057-NG
314-BP). The dark blue line on the graph is showing the ability of Recombinant Human BMP-4 (ng/mL) to induce alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line." class="big_lightbox" target="_blank"> Bioactivity Noggin [Unconjugated]
3718-FB) and Recombinant Human Noggin (Catalog # 6057-NG), along with the other reagents listed in the brain organoid culture recipe. Cerebral organoids were stained for Syto6 (blue), Pax6 (red), and Vimentin (green). (A) Image taken at 4x magnification. (B) An enlarged view of the area shown within the white box in part A of the figure. (C) Image taken at 15x magnification. Images courtesy of LifeCanvas Technologies. " class="big_lightbox" target="_blank"> Bioactivity Noggin [Unconjugated]
brain organoid culture recipe. (A) Representative brightfield image of day 30 iPSC-derived cerebral organoids. (B) Cerebral organoids stained for beta III-tubulin (green) and Prox1 (red), and counterstained with DAPI (blue)." class="big_lightbox" target="_blank"> Bioactivity Noggin [Unconjugated]
Species: Hu
Applications: Bioactivity
Recombinant Mouse Noggin Prot ...
Recombinant Mouse Noggin Protein
1967-NG
1967-NG) inhibits recombinant human BMP-4-induced alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line. The ED50 for this effect is 0.06-0.3 µg/mL in the presence of 50 ng/mL of recombinant human BMP-4 (314-BP)." class="big_lightbox" target="_blank"> Bioactivity Noggin [Unconjugated]
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Mouse Noggin (aa ...
Recombinant Mouse Noggin (aa 28-23...
6997-NG
314-BP)." class="big_lightbox" target="_blank"> Bioactivity Noggin [Unconjugated]
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  

Description

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 9241
Alternate Names
  • noggin
  • SYM1
  • symphalangism 1 (proximal)
  • synostoses (multiple) syndrome 1
  • SYNS1

Research Areas for Noggin

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Stem Cell Markers
Stem Cell Signaling Pathway