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NKX2.2 Products

Antibodies
NKX2.2 Antibody - BSA Free
NKX2.2 Antibody - BSA Free
NBP1-82554
Species: Hu, Mu, Rt
Applications: WB, ChIP, IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
NKX2.2 Antibody (883411) [Unc ...
NKX2.2 Antibody (883411) [Unconjug...
MAB8167
HAF018). A specific band was detected for NKX2.2 at approximately 35 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot NKX2.2 Antibody (883411) [Unconjugated]
NL007) and counterstained with DAPI (blue). Specific staining was localized to nuclei. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry NKX2.2 Antibody (883411) [Unconjugated]
NL007) and counterstained with DAPI (blue). Specific staining was localized to nuclei. View our protocol for Fluorescent ICC Staining of Stem Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry NKX2.2 Antibody (883411) [Unconjugated]
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Mouse Monoclonal
Lysates
NKX2.2 Overexpression Lysate
NKX2.2 Overexpression Lysate
NBL1-13661
Species: Hu
Applications: WB
Proteins
NKX2.2 Recombinant Protein An ...
NKX2.2 Recombinant Protein Antigen
NBP1-82554PEP
Species: Hu
Applications: AC

Description

Nkx2.2, or Homeobox protein Nkx-2.2, consists of a 273 amino acid isoform that is 30 kDa, and is involved in controlling and maintaining the expression of genes within pancreatic endocrine cells and axons. Current research is being conducted on the relationship between Nkx2.2 and a variety of diseases and disorders, including glioma, neuronitis, maturity-onset diabetes, pancreatitis, Partington syndrome, sarcoma, gastrointestinal neuroendocrine tumor, acute lymphoblastic leukemia, multiple sclerosis, and carcinoid tumors. The protein has been linked to the Wnt, Hedgehog, and notch pathways, as well as regulation of beta-cell development and gene expression. NKx2.2 interacts with several other proteins, including OLIG2, HDAC1, SIN3A, FOXA2, and FOXO1.

Bioinformatics

Uniprot Human
Human
Human
Product By Gene ID 4821
Alternate Names
  • Homeobox protein NK-2 homolog B
  • NK-2 (Drosophila) homolog B
  • NK2 homeobox 2
  • NK2 transcription factor related, locus 2 (Drosophila)
  • NK2 transcription factor related, locus 2
  • NK2 transcription factor-like protein B
  • Nkx2.2
  • NKX2.2homeobox protein Nkx-2.2
  • NKX2BNK-2 homolog B