WB, Flow, IHC, CyTOF-readyHost:
Species: Cm, RM
PVRL4, also known as Poliovirus receptor-related protein 4, is a 510 amino acid protein that is 55 kDa, predominantly expressed in placenta and breast carcinoma, is a single-pass type I membrane protein involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with PVRL2/nectin-1, and oes not act as receptor for alpha-herpesvirus entry into cells. Disease research is being performed in relation to this protein and ectodermal dysplasia, syndactyly, ectodermal dysplasia-syndactyly syndrome 1, measles, ovarian cancer, breast carcinoma, lung cancer, and carcinoma. The PVRL4 protein has shown an interaction with PVRL1, MLLT4, PICK1, TIGIT, PARD3, PVRL3, and PVRL2 in Adherens junctions interactions, Nectin/Necl trans heterodimerization, Cell junction organization, Cell-Cell communication, Cell-cell junction organization, Sertoli-Sertoli Cell Junction Dynamics, and Epithelial Adherens Junctions pathways.
|Product By Gene ID
- Ig superfamily receptor LNIR
- poliovirus receptor-related protein 4
- LNIRnectin 4
- poliovirus receptor-related 4
PTMs for Nectin-4/PVRL4
Learn more about PTMs related to Nectin-4/PVRL4.Biotinylation
Bioinformatics Tool for Nectin-4/PVRL4
Discover related pathways, diseases and genes to Nectin-4/PVRL4. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.