Muscle Phosphofructokinase/PFKM/PFK-1 Products

Antibodies
Muscle Phosphofructokinase/PF ...
Muscle Phosphofructokinase/PFKM/PF...
NBP1-87293
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Muscle Phosphofructokinase/PF ...
Muscle Phosphofructokinase/PFKM/PF...
NBP2-32169
Species: Hu, Mu, Canine, Equine, Feline, Guinea Pig, Primate, Chinese Hamster, Monkey
Applications: WB, IP
Host: Rabbit Polyclonal
Muscle Phosphofructokinase/PF ...
Muscle Phosphofructokinase/PFKM/PF...
MAB7687
Species: Hu, Mu, Rt
Applications: WB, Simple Western
Host: Mouse Monoclonal
Antibody Pairs
Muscle Phosphofructokinase/PF ...
Muscle Phosphofructokinase/PFKM/PF...
H00005213-PW1
Species: Hu
Applications: WB, IP
Lysates
Muscle Phosphofructokinase/PF ...
Muscle Phosphofructokinase/PFKM/PF...
H00005213-T01
Species: Hu
Applications: WB
Muscle Phosphofructokinase/PF ...
Muscle Phosphofructokinase/PFKM/PF...
NBL1-14316
Applications: WB
Proteins
Muscle Phosphofructokinase/PF ...
Muscle Phosphofructokinase/PFKM/PF...
NBP1-87293PEP
Species: Hu
Applications: AC
Muscle Phosphofructokinase/PF ...
Muscle Phosphofructokinase/PFKM/PF...
NBP1-44494
Species: Hu
Applications: PAGE
RNAi
Muscle Phosphofructokinase/PF ...
Muscle Phosphofructokinase/PFKM/PF...
H00005213-R03
Species: Hu

Description

Phosphofructokinases (PFK) are regulatory glycolytic enzymes that convert fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. Human PFK-1 is tetrameric and isoenzymes include PFK-1 muscle (PFKM, PFK-A), PFK-1 liver (PFKL, PFK-B) and PFK-1 platelet (PFKP, PFK-C, PFKF). PFK-1 is inhibited by ATP and citrate (from the tricarboxylic acid cycle). PFK-1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose 2,6-bisphosphate, which is produced by PFK-2 from the same substrate, fructose 6-phosphate. PFK-2 is bifunctional and a key regulator for PFK-1. PFK-2 catalyzes the synthesis of fructose 2,6-bisphosphate and contains fructose 2,6-biphosphatase activity that catalyzes the degradation of fructose 2,6-bisphosphate. PFK-2 is dimeric and isoenzymes include PFK-2 liver (PFKFB1, PFRX), PFK-2 cardiac (PFKFB2), PFK-2 placental (PFKFB3, inducible PFK-2) and PFK-2 testis (PFKFB4).

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 5213
Alternate Names
  • EC 2.7.1,6-phosphofructo-1-kinase
  • GSD7
  • Phosphohexokinase
  • EC 2.7.1.11
  • Phosphofructokinase-M
  • PFKX
  • phosphohexokinase
  • PFK-A
  • phosphofructokinase-M
  • Phosphofructokinase 1
  • PFKA
  • Phosphofructo-1-kinase isozyme A
  • PFK1
  • phosphofructokinase, polypeptide X
  • MGC8699
  • PFK-1
  • 6-phosphofructokinase, muscle type
  • phosphofructokinase, muscle

Research Areas for Muscle Phosphofructokinase/PFKM/PFK-1

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism

PTMs for Muscle Phosphofructokinase/PFKM/PFK-1

Learn more about PTMs related to Muscle Phosphofructokinase/PFKM/PFK-1.

Phosphorylation
Oxidation

Bioinformatics Tool for Muscle Phosphofructokinase/PFKM/PFK-1

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