LYVE-1 Products

Antibodies
LYVE-1 Antibody [Unconjugated ...
LYVE-1 Antibody [Unconjugated]
AF2125
Species: Mu
Applications: WB, IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
LYVE-1 Antibody
LYVE-1 Antibody
NB600-1008
Species: Mu, Rt
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
Antibody Packs
LYVE-1 Antibody Pack
LYVE-1 Antibody Pack
NB100-939
Species: Hu, Mu
Applications: WB, IHC
Host: Rabbit
Lysates
LYVE-1 Overexpression Lysate ...
LYVE-1 Overexpression Lysate (Native)
NBL1-12770
Species: Hu
Applications: WB
Proteins
Recombinant Human LYVE-1 Prot ...
Recombinant Human LYVE-1 Protein, CF
2089-LY
Species: Hu
Applications: Binding Activity
Formulation Catalog # Availability Price  
Recombinant Mouse LYVE-1 Prot ...
Recombinant Mouse LYVE-1 Protein, CF
2125-LY
Species: Mu
Applications: Binding Activity
Formulation Catalog # Availability Price  
LYVE-1 Blocking Peptide
LYVE-1 Blocking Peptide
NB100-725PEP
Species: Mu
RNAi
LYVE-1 RNAi
LYVE-1 RNAi
H00010894-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

LYVE1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module, the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Mouse
Product By Gene ID 10894
Alternate Names
  • CRSBP-1
  • CRSBP1
  • Hyaluronic acid receptor
  • lymphatic vessel endothelial hyaluronic acid receptor 1
  • Extracellular link domain-containing protein 1
  • extracellular link domain-containing 1
  • Cell surface retention sequence-binding protein 1
  • cell surface retention sequence binding protein-1
  • extracellular link domain containing 1
  • LYVE-1XLKD1
  • HAR
  • lymphatic vessel endothelial hyaluronan receptor 1

Research Areas for LYVE-1

Find related products by research area and learn more about each of the different research areas below.

Endosome Markers
Endothelial Cell Markers
Immunology

PTMs for LYVE-1

Learn more about PTMs related to LYVE-1.

Sulphation
Glycosylation
Acetylation

Bioinformatics Tool for LYVE-1

Discover related pathways, diseases and genes to LYVE-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related LYVE-1 Blog Posts

Check out the latest blog posts on LYVE-1.
Meningeal lymphatics: recent discovery defying the concept of central nervous system 'immune privilege'
By Jennifer Sokolowski, MD, PhD. Identification and characterization of meningeal lymphaticsThe recent discovery of a lymphatic system in the meninges surrounding the brain and spinal cord has spurred a surge of int...    Read more.
Read more LYVE-1 related blogs.