Legumain/Asparaginyl Endopeptidase Products

Antibodies
Legumain/Asparaginyl Endopept ...
Legumain/Asparaginyl Endopeptidase...
AF2199
Species: Hu
Applications: WB, IP
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Legumain/Asparaginyl Endopept ...
Legumain/Asparaginyl Endopeptidase...
MAB2058
Species: Mu
Applications: WB
Host: Rat Monoclonal
Legumain/Asparaginyl Endopept ...
Legumain/Asparaginyl Endopeptidase...
AF2058
Species: Mu
Applications: WB
Host: Sheep Polyclonal
Antibody Pairs
Legumain/Asparaginyl Endopept ...
Legumain/Asparaginyl Endopeptidase...
H00005641-PW1
Species: Hu
Applications: WB, IP
Legumain/Asparaginyl Endopept ...
Legumain/Asparaginyl Endopeptidase...
H00005641-AP11
Species: Hu
Applications: S-ELISA
Legumain/Asparaginyl Endopept ...
Legumain/Asparaginyl Endopeptidase...
H00005641-PW2
Species: Hu
Applications: WB, IP
Lysates
Legumain/Asparaginyl Endopept ...
Legumain/Asparaginyl Endopeptidase...
H00005641-T01
Species: Hu
Applications: WB
Legumain/Asparaginyl Endopept ...
Legumain/Asparaginyl Endopeptidase...
NBL1-12508
Applications: WB
Legumain/Asparaginyl Endopept ...
Legumain/Asparaginyl Endopeptidase...
NBP2-11310
Applications: WB
Proteins
Legumain/Asparaginyl Endopept ...
Legumain/Asparaginyl Endopeptidase...
H00005641-P01
Species: Hu
Applications: WB, ELISA, PA
Legumain/Asparaginyl Endopept ...
Legumain/Asparaginyl Endopeptidase...
NBP1-87793PEP
Species: Hu
Applications: AC
Legumain/Asparaginyl Endopept ...
Legumain/Asparaginyl Endopeptidase...
NBP2-52295
Species: Mu
Applications: PAGE
RNAi
Legumain/Asparaginyl Endopept ...
Legumain/Asparaginyl Endopeptidase...
H00005641-R02
Species: Hu
Legumain/Asparaginyl Endopept ...
Legumain/Asparaginyl Endopeptidase...
H00005641-R01
Species: Hu

Description

Legumain encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 5641
Alternate Names
  • Asparaginyl endopeptidase
  • cysteine protease 1
  • protease, cysteine, 1 (legumain)
  • AEP
  • LGMN1
  • PRSC1EC 3.4.22.34
  • Protease, cysteine 1
  • legumain

Pathways for Legumain/Asparaginyl Endopeptidase

View related products by pathway and learn more about each of the pathways below.

Cell Growth
Cell Adhesion
Regeneration
Cell Proliferation

Research Areas for Legumain/Asparaginyl Endopeptidase

Find related products by research area and learn more about each of the different research areas below.

Cancer

Bioinformatics Tool for Legumain/Asparaginyl Endopeptidase

Discover related pathways, diseases and genes to Legumain/Asparaginyl Endopeptidase. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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