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HAF017). A specific band was detected for JAM‑C at approximately 36-38 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system." class="big_lightbox" target="_blank">
1074-VJ), immobilized onto a microplate previously coated with Goat Anti-Human IgG Fc (Catalog # G-102-C), supports the adhesion of the J45.01 human acute lymphoblastic leukemia T lymphocyte cell line in a dose-dependent manner (orange line), as measured by endogenous cellular lysosomal acid phosphatase activity. Adhesion elicited by Recombinant Human JAM-B Fc Chimera (0.2 µg/mL) is neutralized (green line) by increasing concentrations of Human JAM-C Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1189). The ND50 is typically 2-8 µg/mL." class="big_lightbox" target="_blank">
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. [provided by RefSeq]
![Immunohistochemistry JAM-C Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/JAM-C_AF1213_Immunohistochemistry_10165.jpg)
![Western Blot JAM-C Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/JAMC_AF1189_Western_Blot_21522.jpg)
![Immunocytochemistry JAM-C Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/JAMC_AF1213_Immunocytochemistry__Immunofluorescence_17388.jpg)
![Immunohistochemistry JAM-C Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af1213_mouse-jam-c-affinity-purified-polyclonal-ab-immunohistochemistry-12122025828283.jpg)
![Immunohistochemistry JAM-C Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af1213_mouse-jam-c-affinity-purified-polyclonal-ab-immunohistochemistry-121220258155011.jpg)
![Simple Western JAM-C Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/JAMC_AF1189_Simple_Western_21435.jpg)
![Neutralization JAM-C Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/JAM-C_AF1189_Block_Neutralize_8763.jpg)
