Integrin beta 4/CD104 Products

Antibodies
Proteins
Recombinant Human Integrin be ...
Recombinant Human Integrin beta 4/...
NBP2-61461
Species: Hu
Applications: PAGE
Integrin beta 4/CD104 Recombi ...
Integrin beta 4/CD104 Recombinant ...
NBP2-38297PEP
Species: Hu
Applications: AC
Integrin beta 4/CD104 Recombi ...
Integrin beta 4/CD104 Recombinant ...
NBP2-38298PEP
Species: Hu
Applications: AC

Description

Integrin beta 4 is a glycoprotein which associates with the a6 integrin to form the a6/b4 complex. Integrin alpha 6/beta 4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Defects in Integrin beta 4 gene are a cause of epidermolysis bullosa letalis with pyloric atresia (EB PA); also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. EB-PA is characterized by mucocutaneous fragility and gastrointestinal atresia, which most commonly affects the pylorus. Moreover, defects in Integrin beta 4 gene are a cause of generalized atrophic benign epidermolysis bullosa (GABEB). This nonlethal form of junctional epidermolysis bullosa is characterized by life long blistering of the skin, associated with hair and tooth abnormalities.

Bioinformatics

Entrez Mouse
Rat
Human
Uniprot Mouse
Human
Human
Human
Product By Gene ID 3691
Alternate Names
  • CD104 antigen
  • CD104
  • GP150
  • integrin beta-4 subunit
  • integrin beta-4
  • integrin, beta 4

Research Areas for Integrin beta 4/CD104

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Immunology
Phospho-Specific
Signal Transduction

Bioinformatics Tool for Integrin beta 4/CD104

Discover related pathways, diseases and genes to Integrin beta 4/CD104. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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