ILT4/CD85d/LILRB2 Products

Antibodies
ILT4/CD85d/LILRB2 Antibody [U ...
ILT4/CD85d/LILRB2 Antibody [Unconj...
AF2078
Species: Hu
Applications: WB, Flow, CyTOF-ready, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
ILT4/CD85d/LILRB2 Antibody
ILT4/CD85d/LILRB2 Antibody
NBP1-98554
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
ILT4/CD85d/LILRB2 Overexpress ...
ILT4/CD85d/LILRB2 Overexpression L...
H00010288-T01
Species: Hu
Applications: WB
ILT4/CD85d/LILRB2 Overexpress ...
ILT4/CD85d/LILRB2 Overexpression L...
NBL1-12527
Applications: WB
ILT4/CD85d/LILRB2 Overexpress ...
ILT4/CD85d/LILRB2 Overexpression L...
NBL1-12528
Applications: WB
Proteins
Recombinant Human ILT4/CD85d/ ...
Recombinant Human ILT4/CD85d/LILRB...
H00010288-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human ILT4/CD85d/ ...
Recombinant Human ILT4/CD85d/LILRB...
H00010288-G01
Species: Hu
RNAi
ILT4/CD85d/LILRB2 RNAi
ILT4/CD85d/LILRB2 RNAi
H00010288-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

LILRB2, also known as Leukocyte immunoglobulin-like receptor subfamily B member 2, has 2 isoforms, a 598 amino acid isoform that is 65 kDa and a 597 amino acid isoform that is approx. 65 kDa; expressed on monocytes and B-cells, and at lower levels on dendritic cells and in natural killer (NK) cells; as a receptor binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response; also competes with CD8A for binding to class I MHC antigens and inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. Disease research is currently being performed with relation to LILRB2 and herpes simplex, chronic lymphocytic leukemia, lymphocytic leukemia, and leukemia. Interactions with this protein have been shown to involve PTPN6, FCGR1A, HLA-F, HLA-G, CD1D and other proteins in osteoclast differentiation, immune-regulatory interactions between a lymphoid and a non-lymphoid cell, adaptive immune system, and immune system pathways.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 10288
Alternate Names
  • CD85d antigen
  • ILT-4
  • leukocyte immunoglobulin-like receptor subfamily B member 2 soluble isoform
  • Monocyte/macrophage immunoglobulin-like receptor 10
  • leukocyte immunoglobulin-like receptor subfamily B member 2
  • Leukocyte immunoglobulin-like receptor 2
  • Ig-like transcript 4
  • Immunoglobulin-like transcript 4
  • LIR-2subfamily A (with TM domain), member 6
  • MIR10LILRA6
  • LIR2CD85D
  • ILT4CD85d
  • CD85 antigen-like family member D
  • member 2
  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains)

PTMs for ILT4/CD85d/LILRB2

Learn more about PTMs related to ILT4/CD85d/LILRB2.

Phosphorylation
Acetylation

Bioinformatics Tool for ILT4/CD85d/LILRB2

Discover related pathways, diseases and genes to ILT4/CD85d/LILRB2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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