IL-12 p70/IL-12A Products

Antibodies
IL-12 p70/IL-12A Antibody (24 ...
IL-12 p70/IL-12A Antibody (24910)
MAB219
Species: Hu
Applications: WB, Neut
Host: Mouse Monoclonal
IL-12 p70/IL-12A Antibody (48 ...
IL-12 p70/IL-12A Antibody (48110)
MAB419
Species: Mu
Applications: WB, ELISA(Cap)
Host: Rat Monoclonal
IL-12 p70/IL-12A Antibody (24 ...
IL-12 p70/IL-12A Antibody (24945) ...
MAB611
Species: Hu
Applications: ELISA(Cap), ICC
Host: Mouse Monoclonal
Lysates
IL-12 p70/IL-12A Overexpressi ...
IL-12 p70/IL-12A Overexpression Ly...
NBL1-11900
Applications: WB
IL-12 p70/IL-12A Overexpressi ...
IL-12 p70/IL-12A Overexpression Ly...
NBP2-10135
Applications: WB
Proteins
IL-12 p70/IL-12A Recombinant ...
IL-12 p70/IL-12A Recombinant Prote...
NBP1-85564PEP
Species: Hu
Applications: AC
IL-12 p70/IL-12A Recombinant ...
IL-12 p70/IL-12A Recombinant Protein
P3997
Species: Hu
Applications: Func, PAGE

Description

Interleukin-12, or IL-12, also known as natural killer cell stimulatory factor (NKSF) and cytotoxic lymphocyte maturation factor (CLMF), is a pleiotropic cytokine that affects both natural killer (NK) cells and T lymphocytes. IL-12 is a heterodimer of subunit IL-12A p35 and subunit IL-12B p40 that is secreted by a wide variety of antigen presenting cells (APCs), including phagocytes, B cells and Langerhans cells. It is involved in mediating many aspects of antiviral immunity. In addition to stimulating T helper cell development, IL-12 is a potent inducer of interferon-gamma (IFN-gamma) production by T cells and NK cells. Increased IL-12 production is a consequence of EBV, CMV, LCMV or HSV infection. While it is unclear what separate effects can be attributed to each IL-12 subunit, evidence suggests IL-12A p35 is the biologically active component responsible for signal transduction via the IL-12 receptor.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 3592
Alternate Names
  • NF cell stimulatory factor chain 1
  • p35
  • natural killer cell stimulatory factor 1, 35 kD subunit
  • NK cell stimulatory factor chain 1
  • interleukin-12 subunit alpha
  • IL-12 subunit p35
  • interleukin-12 alpha chain
  • CLMF p35
  • interleukin 12, p35
  • NKSF1
  • IL-12, subunit p35
  • Cytotoxic lymphocyte maturation factor 35 kDa subunit
  • p35
  • interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocytematuration factor 1, p35)

Research Areas for IL-12 p70/IL-12A

Find related products by research area and learn more about each of the different research areas below.

Immunology
Innate Immunity

PTMs for IL-12 p70/IL-12A

Learn more about PTMs related to IL-12 p70/IL-12A.

Phosphorylation
Deacetylation
Methylation

Bioinformatics Tool for IL-12 p70/IL-12A

Discover related pathways, diseases and genes to IL-12 p70/IL-12A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.