GSK-3 beta Products

Antibodies
GSK-3 beta Antibody (1253C) [ ...
GSK-3 beta Antibody (1253C) [Uncon...
MAB8934
Species: Hu
Applications: WB, Simple Western, ICC
Host: Rabbit Monoclonal
GSK-3 beta Antibody
GSK-3 beta Antibody
NBP1-31353
Species: Hu, Mu, Rt, Bovine, Porcine, Sheep
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
GSK-3 beta Overexpression Lys ...
GSK-3 beta Overexpression Lysate (...
NBL1-11362
Applications: WB
GSK-3 beta Overexpression Lys ...
GSK-3 beta Overexpression Lysate (...
H00002932-T05
Applications: WB
Proteins
GSK-3 beta Recombinant Protei ...
GSK-3 beta Recombinant Protein
NBP2-51519
Species: Hu
Applications: PAGE
GSK-3 beta Recombinant Protei ...
GSK-3 beta Recombinant Protein Ant...
NBP1-90359PEP
Species: Hu
Applications: AC
GSK-3 beta Recombinant Protei ...
GSK-3 beta Recombinant Protein
NBP2-52221
Species: Hu
Applications: PAGE
RNAi
GSK-3 beta RNAi
GSK-3 beta RNAi
H00002932-R02
Species: Hu

Description

Glycogen synthase kinase 3beta (GSK-3 beta) is a Serine/Threonine protein kinas involved in the insulin and wingless pathways (1-2). Originally identified as a regulator of glycogen synthase, it has been shown to regulate a diverse array of cellular functions. GSK-3 beta activity is down regulated by phosphorylation on Serine 9 by PKB, or activated by phosphorylation on Tyrosine 216. Once activated, the protein can phosphorylate p53, c-jun, heat shock factor-1 and cyclin D1 (3-4). It is also known to phosphorylate Tau in Allzheimer's disease. Additionally, increased GSK-3 beta protein levels are found in Alzheimer's disease brains.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 2932
Alternate Names
  • EC 2.7.11
  • GSK3beta isoform
  • glycogen synthase kinase-3 beta
  • EC 2.7.11.26
  • GSK-3 beta
  • glycogen synthase kinase 3 beta

Research Areas for GSK-3 beta

Find related products by research area and learn more about each of the different research areas below.

Cancer
Hypoxia
Lipid and Metabolism
mTOR Pathway
Phospho-Specific
Protein Kinase
Signal Transduction
Wnt Signaling Pathway

PTMs for GSK-3 beta

Learn more about PTMs related to GSK-3 beta.

Phosphorylation
Ubiquitination
Reduction
Cleavage
Glycosylation
Oxidation

Bioinformatics Tool for GSK-3 beta

Discover related pathways, diseases and genes to GSK-3 beta. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related GSK-3 beta Blog Posts

Check out the latest blog posts on GSK-3 beta.
Epithelial-Mesenchymal Transition (EMT) Markers
Epithelial-Mesenchymal Transition (EMT) is the trans-differentiation of stationary epithelial cells into motile mesenchymal cells. During EMT, epithelial cells lose their junctions and apical-basal polarity, reorganize their cytoskeleton, undergo a...    Read more.
Read more GSK-3 beta related blogs.