FABP2/I-FABP Products

Description

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance.

Bioinformatics

Entrez	14079 Mouse 2169 Human
Uniprot	NM_000134 Human NP_000125 Human P12104 Human
Product By Gene ID	2169
Alternate Names	FABPI fatty acid binding protein 2, intestinal Fatty acid-binding protein 2 fatty acid-binding protein, intestinal I-FABPMGC133132 Intestinal-type fatty acid-binding protein

Research Areas for FABP2/I-FABP

Find related products by research area and learn more about each of the different research areas below.

Cholesterol Metabolism
Lipid and Metabolism