ELA3A Products

Description

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1.

Bioinformatics

Entrez	10136 Human
Uniprot	AAH07028 Human NM_005747 Human P09093 Human
Product By Gene ID	10136
Alternate Names	chymotrypsin-like elastase family member 3A chymotrypsin-like elastase family, member 3A EC 3.4.21 EC 3.4.21.70 ELA3A ELA3elastase 1 elastase 3A, pancreatic (protease E) elastase 3A, pancreatic Elastase IIIA elastase-3A Elastase-3A Protease E

Research Areas for ELA3A

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Lipid and Metabolism