CXCR4 Products

CXCR4 Antibody (247506) [Unco ...
CXCR4 Antibody (247506) [Unconjuga...
Species: Mu
Applications: Flow, IHC, B/N, CyTOF-ready, ICC/IF
Host: Rat Monoclonal
CXCR4 Antibody
CXCR4 Antibody
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
Human CXCR4 ELISA Kit (Colori ...
Human CXCR4 ELISA Kit (Colorimetric)
Species: Hu
Applications: ELISA, S-ELISA
CXCR4 Overexpression Lysate
CXCR4 Overexpression Lysate
Species: Hu
Applications: WB
CXCR4 Antibody Blocking Pepti ...
CXCR4 Antibody Blocking Peptide
Applications: AC
CXCR4 Antibody Blocking Pepti ...
CXCR4 Antibody Blocking Peptide
Applications: AC
CXCR4 Antibody Blocking Pepti ...
CXCR4 Antibody Blocking Peptide
Applications: AC


CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lympho- and myelopoiesis, cardiogenesis, blood vessel formation and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2. The 12G5 antibody has been reported to block CD4-independent infection by HIV-2 and CD4-dependent infection by some T cell-tropic isolates of HIV-1.


Entrez Mouse
Uniprot Human
Product By Gene ID 7852
Alternate Names
  • CD184
  • chemokine (C-X-C motif) receptor 4
  • chemokine (C-X-C motif), receptor 4 (fusin)
  • C-X-C chemokine receptor type 4
  • CXC-R4
  • CXCR-4
  • D2S201ESDF-1 receptor
  • FB22
  • Fusin
  • fusin
  • HSY3RR
  • LAP3
  • LCR1
  • LESTRCD184 antigen
  • Leukocyte-derived seven transmembrane domain receptor
  • leukocyte-derived seven-transmembrane-domain receptor
  • lipopolysaccharide-associated protein 3
  • neuropeptide Y receptor Y3
  • NPYR
  • NPYY3R
  • pCXCR4
  • seven transmembrane helix receptor
  • seven-transmembrane-segment receptor, spleen
  • Stromal cell-derived factor 1 receptor

Research Areas for CXCR4

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Cytokine Research
Growth and Development
Innate Immunity
Neuronal Cell Markers
Signal Transduction

Bioinformatics Tool for CXCR4

Discover related pathways, diseases and genes to CXCR4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related CXCR4 Blog Posts

Check out the latest blog posts on CXCR4.
Understanding CXCR4 and SDF1
CXCR4 (C-X-C chemokine receptor type 4) is a member of the G-protein coupled receptor (GPCR1) family. It is expressed as a multipass membrane protein in several tissues where it acts as the receptor for the C-X-C chemokine CXCL12/SDF-1. This ligand in...    Read more.
CXCR4 Studies on Neural and Stem Cells
The CXCR4 (C-X-C chemokine receptor type 4) protein is one member of the G-protein coupled receptor (GPCR1) family. As a multipass membrane protein that is found in several tissues, it is the receptor for the C-X-C chemokine CXCL12/SDF-1. The CXCR4 li...    Read more.
LAMP2: Protector of the lysosome
LAMP2 belongs to the family of membrane glycoproteins who confer selectins with carbohydrate ligands. LAMP2 has been implicated in tumor cell metastasis, as well as overall protection, maintenance, and adhesion of the lysosome. It appears that LAMP2 m...    Read more.
Stemness is responsible for onset and metastasis of colorectal cancer
By Jamshed Arslan, Pharm. D., PhD. Colorectal cancer stem cells are a rare subpopulation of colorectal cancer cells that can self-renew and initiate and sustain tumor growth when transplanted into an animal host.1,2 C...    Read more.
Read more CXCR4 related blogs.