Autophagy Products

Antibody Packs
Autophagy Antibody Pack
Autophagy Antibody Pack
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Autophagy Antibody Pack
Autophagy Antibody Pack
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P

Description

Autophagy includes sample aliquots to many different autophagy related proteins. Autophagy can be understood as a cell recycling system on its most basic level. Components of the cytoplasm are sequestered and moved in the lysosome where they are broken down into their basic components and returned to the cytosol for reuse. For information on the individual antibodies contained in this pack, please click on their links below.

Bioinformatics

Product By Gene ID 8678
Alternate Names
  • ATG6 autophagy related 6 homolog
  • Protein GT197
  • Coiled-coil myosin-like BCL2-interacting protein
  • GT197
  • beclin 1 (coiled-coil, moesin-like BCL2 interacting protein)
  • beclin1
  • VPS30
  • beclin-1
  • ATG6
  • beclin 1 (coiled-coil, moesin-like BCL2-interacting protein)
  • beclin 1, autophagy related

Research Areas for Autophagy

Find related products by research area and learn more about each of the different research areas below.

Autophagy

Bioinformatics Tool for Autophagy

Discover related pathways, diseases and genes to Autophagy. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Autophagy Blog Posts

Check out the latest blog posts on Autophagy.
Why LC3B Antibodies Make Ideal Autophagosomes Membrane Markers
The human form of microtubule-associated protein light chain 3 (LC3) is expressed as 3 splice variants; LC3A, LC3B and LC3C (He et al., 2003). LC3B is a subunit of the MAP1A and MAP1B microtubule-binding proteins and plays a central role autophagosome...    Read more.
Three things everyone studying autophagy should know
Novus Biologicals' antibodies are the gold standard to monitor autophagy and detect LC3 expression. The recently published Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition) comprehensively details methods...    Read more.
ATG4C - A regulator of the early steps of autophagosome assembly
Autophagy is an important cellular process that maintains homeostasis by degrading and recycling damaged proteins and organelles. Autophagy receptors, such as p62/SQSTM1, recognize these intracellular cargo and mediate their engulfment by the doubl...    Read more.
LAMP2 - a marker of lysosomes and late endosomes
Lysosomes are membrane-bound organelles responsible for the degradation of various biological macromolecules. Vesicles containing hydrolytic enzymes bud from the Golgi and fuse with endosomes to form the mature lysosome capable of breaking down va...    Read more.
Beclin 1 - a key regulator of autophagosome formation
The Beclin 1 protein is a central regulator of autophagy in mammalian cells. Autophagy is an essential process used to maintain cellular homeostasis by degrading and recycling cellular components such as damaged or worn out organelles and macromole...    Read more.
ATG9A - early marker autophagosome assembly
ATG9A is the only essential integral membrane protein involved in autophagy. ATG9A contains six transmembrane domains and initiates the assembly of autophagosomes. The autophagosome is a double-membrane structure that engulfs and eventually degrade...    Read more.
LC3B - a novel marker for autophagosome
Autophagy, also known as macroautophagy, supplies alternative fuel for cells that are under environmental stress conditions (including starvation, growth factor deprivation, and hypoxia). This highly regulated and catabolic cell process recycles a...    Read more.
Comprehensive Autophagy Research Tools - New Catalog Available Now!
Autophagy, a protein degradation process through autophagosome-lysosomal pathway, is important for cellular homeostasis and plays a role in many diseases. To help researchers learn more about this process and the products available for its study, N...    Read more.
ATG5: Roles in Cellular Defense
ATG5, or Autophagy Related 5, is a protein crucial for autophagy. Autophagy is a mechanism in which dysfunctional or pathogenic cells or cellular components are degraded and sometimes recycled. This process happens when ATG5 conjugates with another pr...    Read more.
ATG5, Autophagy and Apoptosis
ATG5 is a member of the ATG family that regulates autophagy, the evolutionary conserved homeostatic response to a diverse variety of self- and foreign-originating cellular stresses. ATG5 is ubiquitously expressed in cells and found co-localized with c...    Read more.
Wide Ranging Uses for the Autophagy Marker - Beclin-1 Antibody
Beclin 1 is the first mammalian gene identified as a mediator of autophagy, and plays important roles in development, tumorigenesis, and neurodegeneration. Research with the beclin-1 antibody has revealed that, Beclin 1 is found in complex with the th...    Read more.
PINK1: Promoting Organelle Stability and Preventing Parkinson's disease
PINK1 is a protein serine/threonine kinase (PTK) that protects the organelles from cellular stress and controls selective autophagy to clear damage. Exner, et. al. were among the first to report that PINK1 deficiency in humans was linked to autosomal...    Read more.
LC3: Roles in Autophagy, Apoptosis, Neurological Diseases and Cancer
LC3 is distributed ubiquitously in eukaryotes and is a heavily studied autophagy biomarker that was originally identified as a subunit of MAP1A and MAP1B. Because autophagy is a crucial process for maintaining normal neural networks and function, unde...    Read more.
LC3B: From Autophagy to Cancer
LC3B is subunit component of the LC3 autophagy biomarker associated with microtubule-associated proteins MAP1A and MAP1B and one of the best characterized markers to date. In resting state it is cytosolic, but upon activation, is lapidated and becomes...    Read more.
ATG5: From Autophagy to Alzheimer's Disease
Autophagy is a conserved mechanism whereby cells form double membrane autophagosomes to sequester cytoplasmic components for subsequent destruction by fusion with lysosomes (eukaryotes) or vacuoles (yeast). Targets of autophagy include aging proteins,...    Read more.
Beclin 1: Regulator of Autophagy and Apoptosis
Beclin 1 is the mammalian orthologue of the yeast Apg6/Vps30 gene. Beclin 1 can complement the defect in autophagy present in apg6 yeast strains and stimulate autophagy when overexpressed in mammalian cells (1) and can bind to Bcl2, an important regul...    Read more.
Anti-beclin Antibodies And Autophagy
Antibodies to beclin 1 may help elucidate the significance of this protein and its role in autophagy. Autophagy is the lysosomal degradation of cell constituents. It occurs in malnutrition, enabling the body to recycle cell components to provide metab...    Read more.
Read more Autophagy related blogs.