Apolipoprotein A5 Products

Description

Apolipoprotein A5 (ApoA5) is a minor apolipoprotein, predominantly associated with HDL and and occasionally with VLDL and chylomicrons. ApoA-5 is a useful indicator of plasma triglyceride levels, a major risk factor for coronary artery disease.

Apo A5 is expressed in the plasma and the liver, where it is involved in the early phase of liver regeneration.

APOA5 mutations can lead to increaased susceptibility to familial hypertriglyceridemia (FHTR), a common inherited disorder where VLDL concentrations are elevated in the plasma. This disorder increases the risk of heart disease, obesity, and pancreatitis. APOA5 mutations can also cause hyperlipoproteinemia type 5 (HLPP5), characterized by increased amounts of chylomicrons/VLDL and decreased amounts of LDL/HDL in the plasma. This disorder often leads to a wide array of syndromes, including insulin-dependent diabetes mellitus, contraceptive steroids, alcohol abuse, and glycogen storage disease type 1A

ApoA5 antibodies are useful for studying lipoprotein processing and a variety of cardiac diseases.

Bioinformatics

Entrez	116519 Human
Uniprot	AAI01790.1 Human AAI01790.1 Human NM_052968 Human NM_052968 Human NP_443200 Human NP_443200 Human NP_443200.2 Human NP_443200.2 Human Q6Q788 Human Q6Q788 Human
Product By Gene ID	116519
Alternate Names	APOAV Apo-AV apo-AV APOA-V ApoA-V Apolipoprotein A5 apolipoprotein A-V FLJ97995 MGC126836 RAP3MGC126838 Regeneration-associated protein 3

Research Areas for Apolipoprotein A5

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cholesterol Metabolism
Lipid and Metabolism
Signal Transduction