Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Host: Rat Monoclonal
Applications: WB, IP
ANGPTL3 is a 460 amino acid protein that is found most commonly in the liver, but has also been shown to reside in kidney samples, and contains three domains consisting of a signal peptide, N-terminal coiled-coil and C-terminal Fibrinogen (FBN) like domain. This protein is involved with the lipid metabolism disease pathways in relation to low levels of LDL (low density lipoproteins), HDL (High density lipoproteins), and triglycerides in plasma. This protein plays a role in angiogenesis and has been shown to interact with ITGAV, ITGB3, and ITGA5, and work is being done to study the protein and the related hypobetalipoproteinemia and atherosclerosis involvement.
Research Areas for Angiopoietin-like Protein 3/ANGPTL3
Find related products by research area and learn more about each of the different research areas below.Signal Transduction
Bioinformatics Tool for Angiopoietin-like Protein 3/ANGPTL3
Discover related pathways, diseases and genes to Angiopoietin-like Protein 3/ANGPTL3. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.