Akt1 Products

Antibodies
Akt1 Antibody (3A3)
Akt1 Antibody (3A3)
NBP1-51602
Species: Hu, Mu, Pm
Applications: WB, ELISA, IHC, IHC-P, IP
Host: Mouse Monoclonal
Akt1 Antibody (4D6)
Akt1 Antibody (4D6)
Species: Hu, Mu, Rt, Ca, Mk
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Antibody Pairs
Akt1 Antibody Pair
Akt1 Antibody Pair
H00000207-AP11
Species: Hu
Applications: S-ELISA
Akt1 Antibody Pair
Akt1 Antibody Pair
H00000207-PW1
Species: Hu
Applications: WB, IP
Akt1 Antibody Pair
Akt1 Antibody Pair
H00000207-PW2
Species: Hu
Applications: WB, IP
ELISA Kits
Akt1 [p Ser473] ELISA Kit [HR ...
Akt1 [p Ser473] ELISA Kit [HRP]
KA2151
Species: Hu, Mu, Rt
Akt1 [p Ser473] ELISA Kit [HR ...
Akt1 [p Ser473] ELISA Kit [HRP]
KA2152
Species: Hu, Mu, Rt
Lysates
Akt1 Overexpression Lysate (N ...
Akt1 Overexpression Lysate (Native)
NBP2-09148
Applications: WB
Akt1 Overexpression Lysate (N ...
Akt1 Overexpression Lysate (Native)
NBL1-07441
Applications: WB
Akt1 Overexpression Lysate (N ...
Akt1 Overexpression Lysate (Native)
NBP2-08736
Applications: WB
Proteins
Akt1 Recombinant Protein
Akt1 Recombinant Protein
H00000207-P01
Species: Hu
Applications: WB, ELISA, PA
Akt1 Partial Recombinant Prot ...
Akt1 Partial Recombinant Protein
H00000207-Q02
Species: Hu
Applications: WB, ELISA, PA
Akt1 Partial Recombinant Prot ...
Akt1 Partial Recombinant Protein
H00000207-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Akt1 RNAi
Akt1 RNAi
H00000207-R01V
Species: Hu
Applications: WB, RNAi, RNAi SP
Akt1 RNAi
Akt1 RNAi
H00000207-R02V
Species: Hu
Applications: WB, RNAi, RNAi SP
Akt1 RNAi
Akt1 RNAi
H00000207-R08
Species: Hu
Applications: RNAi, RNAi SP

Description

The serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific. In the developing nervous system AKT is a critical mediator of growth factor induced neuronal survival. Survival factors can suppress apoptosis in a transcription independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene (referenced from entrez gene).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Mouse
Product By Gene ID 207
Alternate Names
  • RAC-PK-alpha
  • EC 2.7.11
  • Proto-oncogene c-Akt
  • RAC-alpha serine/threonine-protein kinase
  • Protein kinase B
  • rac protein kinase alpha
  • PRKBA
  • RAC-ALPHA
  • AKT
  • RACPKB-ALPHA
  • PKBMGC99656
  • EC 2.7.11.1
  • v-akt murine thymoma viral oncogene homolog 1

Research Areas for Akt1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Autophagy
Cancer
Growth and Development
Hypoxia
mTOR Pathway
Neuronal Cell Markers
Phospho-Specific
Signal Transduction

Bioinformatics Tool for Akt1

Discover related pathways, diseases and genes to Akt1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Akt1 Blog Posts

Check out the latest blog posts on Akt1.
AKT1 - Regulating cell growth and survival through phosphorylation
AKT1 is a serine/threonine protein kinase with homology to protein kinase A (PKA) and protein kinase C (PKC). AKT1 contains the central kinase domain sandwiched between a pleckstrin homology domain and a regulatory domain (1). AKT1 is regulated by...    Read more.
Akt1 - a central player in cell survival signaling
Akt1 is one of three isoforms of Akt belonging to the AGC family of serine/threonine kinases (Akt1, Akt2, and Akt3). All Akt isoforms contain an N-terminal Plekstrin Homology (PH) domain, a C-terminal regulatory domain, and a central catalytic kin...    Read more.
AKT1, Scene 1: The Cell Must Go On
Akt1 is a serine/threonine-specific protein kinase involved in many cellular signaling pathways. The major function of this kinase is to mediate cell survival, but it also plays key roles in various other cellular functions such as glycogen synthesis...    Read more.
Caspase 9 and Mitochondrial Apoptosis Regulation
Caspase 9 (also termed ICE-LAP6, Mch6, Apaf-3) is a member of cysteine protease family of caspases and is encoded by the CASP9 gene in humans. Caspase-9 is involved in mitochondrial apoptosis pathway and is an initiator caspase. Pro-caspase-9 is activ...    Read more.
Mapping Signal Transduction with mTOR Antibodies
The protein encoded by mTOR (mammalian target of rapamycin), also known as dTOR in Drosophila, belongs to a family of phosphatidylinositol kinase-related kinases. These kinases regulate fundamental processes of cell growth, proliferation, metabolism...    Read more.
EZH2: Epigenetic Regulation Made Easy!
Enhancer of Zeste homolog 2 (EZH2) is the methyltransferase enzyme responsible for trimethylating lysine 27 on histone H3 to produce H3K27Me3. EZH2 is a polycomb group protein that is an essential epigenetic regulator that is often found deregulated i...    Read more.
Antibodies Targeting the mTOR Pathway for Many Diseases
The mammalian target of rapamycin (mTOR) is a downstream effector of the phosphatidylinositol 3-kinase (PI3K)/Akt (protein kinase B) signaling pathway that mediates cell survival and proliferation. It is increasingly apparent that mTOR signaling impac...    Read more.
AKT Antibody Assays: A Complex Area with an Easy Solution
We at Novus Biologicals place a lot of emphasis on the kinase signaling pathways. Kinases, or phosphotransferase enzymes play a key role in phosphorylation signaling. Over 500 human protein kinases have so far been discovered. They play essential role...    Read more.
The Akt Antibody Plays Many Roles in Cancer Research
There are three human isoforms of the AKT gene, which plays a key role in several signalling pathways. Akt antibody studies have shown the Atk kinases to play a diverse number of roles within the cell, regulating angiogenesis, apoptosis, protein synth...    Read more.
Read more Akt1 related blogs.