ADAM10 Products

Antibodies
Proteins
Recombinant Human ADAM10 Prot ...
Recombinant Human ADAM10 Protein, CF
936-AD
Species: Hu
Applications: EnzAct
Recombinant Mouse ADAM10 Prot ...
Recombinant Mouse ADAM10 Protein, CF
946-AD
Species: Mu
Applications: EnzAct
Recombinant Human ADAM10 Prot ...
Recombinant Human ADAM10 Protein
NBP2-53045
Species: Hu
Applications: PAGE
RNAi
ADAM10 RNAi
ADAM10 RNAi
H00000102-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Proinflammatory cytokine tumor necrosis factor-alpha (TNF-a) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-a, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-a, notch and its ligand delta (1-3). The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively, (1,2,4). ADAM10 mRNA is expressed in a variety of human and bovine tissues (1,4).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Mouse
Product By Gene ID 102
Alternate Names
  • EC 3.4.24
  • CDw156
  • CD156c antigen
  • Mammalian disintegrin-metalloprotease
  • KUZ
  • Kuzbanian protein homolog
  • disintegrin and metalloproteinase domain-containing protein 10
  • kuz
  • a disintegrin and metalloprotease domain 10
  • a disintegrin and metalloproteinase domain 10
  • HsT18717
  • AD10
  • CD156c
  • MADMEC 3.4.24.81
  • ADAM 10
  • ADAM metallopeptidase domain 10

Research Areas for ADAM10

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Signal Transduction

Bioinformatics Tool for ADAM10

Discover related pathways, diseases and genes to ADAM10. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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