Lysosome

Nuclear LC3: Why is it there and what is it doing?

By Christina Towers, PhD.

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Autophagy inhibition in pediatrics: One physician-scientist’s brave decision

By Christina Towers, PhD.

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neurodegeneration

Christina Towers

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Cross-talk between proteasome degradation and lysosomal degradation

By Christina Towers, PhD.

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neurodegeneration

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Chaperone Mediated Autophagy (CMA) does it all!

By Christina Towers, PhD.

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neurodegeneration

HSPA8/HSC71/Hsc70

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Analyzing LC3 in Western blot

Microtubule-associated protein light chain 3 (LC3) is considered one of the definitive markers of autophagy, and its use is widespread in labs throughout the world. Despite its popularity, there are several considerations when employing LC3 antibodies in immunoassays, Western blots in particular.

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Autophagic flux

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