Antibody catalog

Newly Validated Antibodies for Immunocytochemistry

Immunocytochemistry (ICC) is a frequently used technique that allows researchers to determine if an antigen is expressed by specific cellular or sub-cellular compartments via the use of antibodies. Many research-grade antibodies are suitable for ICC analysis, however many are not or have not been tested.

Visit Novus Biologicals at the AACR 101st Annual Meeting

We are excited to announce that we will be exhibiting at the American Association for Cancer Research (AACR) 101st Annual Meeting. AACR brings researchers together from across the globe, and as an international antibody supplier, we at Novus Biologicals are enthusiastic about being part of it! This year's Annual Meeting will be held at the Walter E.

Weekly Update On Happenings In The Novus Antibody Lab

The antibody lab technicians here at Novus Biologicals are constantly busy conducting purifications, conjugations and QC analysis in order to maintain our antibody catalog of over 100,000 products. Just this past week, the lab team conjugated numerous antibodies and tested several newly purified antibody lots.

The Production And Function Of Antibodies – An Overview

Many people enter immunobiology from a different area of research. Although they swiftly learn the protocols and methods of the assays, they may not fully understand the underlying concepts. We at Novus Biologicals realise that not everybody purchasing products from our antibody catalogue has an in-depth knowledge of the “tools of the trade”. For them, and anybody else needing a quick bit of revision, we have put together a few basic notes.

FANCD2 Function And Its Link To Tumour Development

FANCD2 is one of a number of proteins in the FANC group. It undergoes modification in both its normal and disease state; therefore our FANCD2 antibodies are modified and conjugated in various ways for research.

FANCD2 (Fanconi Anaemia Complementation Group D2) is one of several FANC proteins involved with development of Fanconi Anaemia, a genetic disease that increases cell susceptibility to tumour development. In its normal pathway it interacts with several other genes known to cause cancer, for example BRCA1.

NHEJ DNA Repair Mechanisms

DNA repair processes allow cells to identify and correct lesions in the DNA helix. It is normal for these lesions to happen. Environmental processes such as exposure to UV light and chemicals, as well as day-to-day metabolic changes, can cause hundreds of thousands in a day.

Approaching Apoptosis With Antibodies

Not everyone knows how antibodies influence animal life, so this article is, in part, a very brief introduction. Novus Biologicals offers a printed version of their Apoptosis Catalog that contains additional information on apoptotic mechanisms; email promotions@novusbio.com to get a copy.

Antibodies Reveal A Non-apoptotic Role For Uterine Caspase 3

We have seen that antibody research can deliver progress in areas where other methods have not enjoyed such success.

Antibodies To GABA-A Receptor Subunits Unlock Some Of The Secrets Of Autism

Autism is a condition which demands more research - even if some autistic people do not want their condition to be ‘cured’, most would like some of their symptoms to be alleviated.

Fatemi and colleagues (J Autism Dev Disord. 2009, 39(2) pp. 223–230) subjected brain tissue from autistic and control subjects to SDS-PAGE followed by Western blotting and incubation with antibodies to four GABA-A receptor subunits.

Approaching apoptosis with antibodies

Not everyone knows how antibodies influence animal life, so this article is, in part, a very brief introduction. Apoptosis is triggered by a variety of signals and takes place by one of several mechanisms. These involve cell surface receptors, cytokines, tumour necrosis factors, proteins such as Bcl-2, Bax and Apaf-1, the caspase cascade, and apoptosis-inducing factors.

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